Histological Skin Changes After Treatment with 675 nm Laser.

Photobiomodulation, Photomedicine, and Laser Surgery
Giovanni CannarozzoSteven Paul Nisticò

Abstract

Objective: To evaluate the histological effects of a new 675-nm laser device on the skin. Background: Innovative technologies based on physical principles have been proposed in recent years to improve the treatment of aging skin. Laser technology is currently being studied for its potential in skin care treatments. A new 675-nm laser device is being used for the treatment of hyperpigmentation, scars, and various types of wrinkles. Methods: A 42-year-old man underwent a 675-nm RedTouch® laser session for the treatment of aging signs on the neck. Two 2.5-mm biopsies were taken from the treated area and the adjacent area untreated with the laser, 45 days after the procedure. Comparison of the immunohistochemistry findings and assessment of the collagen and elastin fibers were performed by a board-certified dermatopathologist. Results: Skin biopsies revealed histological changes that comprised proliferation of new collagen fibers in the treated area, when compared to that in the untreated areas. Conclusions: Histological analysis suggests that the 675-nm laser has a potential role in stimulating collagen remodeling, with a significant increase in thin and new collagen fibers.

References

Jun 1, 1978·Archivum Histologicum Japonicum = Nihon Soshikigaku Kiroku·L C JunqueiraR Brentani
Nov 1, 1973·Beiträge Zur Pathologie·H PuchtlerL S Valentine
Jan 12, 2001·Journal of Molecular Biology·B LiV Daggett
Jan 1, 1957·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·H M FULLMER, R D LILLIE
Jun 14, 2020·Lasers in Medical Science·Giovanni CannarozzoSteven Paul Nisticò
Aug 25, 2020·Photobiomodulation, Photomedicine, and Laser Surgery·Steven Paul NisticòGiovanni Cannarozzo
Jan 16, 2021·Photobiomodulation, Photomedicine, and Laser Surgery·Giovanni CannarozzoSteven Paul Nisticò

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Methods Mentioned

BETA
biopsy
biopsies
light microscopy

Software Mentioned

RedTouch
Nis Elements D
ImageJ

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