Histological Structure and Vascularity of Hysteroscopically Removed Uterine Septa in Patients With Primary Infertility and Patients With Recurrent Pregnancy Loss

Journal of Minimally Invasive Gynecology
Ghada Abdel Fattah Abdel MoetyMohamed Faisal

Abstract

To examine the histological structure and vascularity of uterine septa in patients with unexplained primary infertility and patients with recurrent pregnancy loss (RPL). Case-control study (Canadian Task Force classification II-2). Kasr Al Aini Hospital, Cairo University, Egypt. A total of 41 patients with uterine septa presenting with either unexplained primary infertility or RPL underwent 3-dimensional (3D) and power Doppler (PD) ultrasound to calculate the septum volume, septal vascularization index (VI), and myometrial VI. Hysteroscopically removed septa were examined histologically for myometrial and fibrous tissue content. Septal characteristics differed between the primary infertility group (24 patients) and the RPL group (17 patients). Mean septal VI was significantly higher in the RPL group compared with the infertility group (18.39% ± 7.57% vs 11.67% ± 4.56%; p = .003), as was septal myometrial area (20.74% ± 5.97% vs 13.57% ± 5.55%; p < .001). In both groups, septal VI was strongly correlated with myometrial VI and myometrial content, but not with fibrous tissue content. Uterine septa of patients with RPL are more vascularized and contain more muscular tissue compared with those of patients with primary unexplained i...Continue Reading

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Apr 21, 2019·BJOG : an International Journal of Obstetrics and Gynaecology·Jfw RikkenM van Wely
May 23, 2021·Reproduction in Domestic Animals = Zuchthygiene·Jair Camargo FerreiraCezinande de Meira

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