Histomorphometry of fresh frozen iliac crest bone biopsies

Calcified Tissue International
D H CarterJ E Aaron

Abstract

Although methods are well established for the rapid histological preparation of fresh frozen soft tissues, they remain inadequate for the preservation of hard tissues. A recent technique for sectioning fresh frozen bone, in which sections can be prepared within an hour, has been applied to undecalcified human iliac crest bone biopsies. Quantitative analysis has shown that the static remodeling variables deduced from frozen sections closely resemble those derived from plastic-embedded sections prepared for routine use by established laboratory procedures. It is concluded that the rapid method is reliable for immediate diagnostic and histomorphometric purposes.

References

May 1, 1979·The Histochemical Journal·J J Johnstone
Mar 1, 1987·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J E Aaron, D H Carter
Mar 1, 1985·Histopathology·A Stevens, J Palmer
Jan 1, 1972·Journal of Clinical Pathology·A D Pearse, D L Gardner
Jan 1, 1970·Acta Anatomica·W A Merz, R K Schenk
Dec 1, 1984·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J E AaronM Peacock

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Citations

Aug 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J N BradbeerJ Reeve
Jan 1, 1993·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·H H McElroyA M Parfitt

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