Histone deacetylase complexes: functional entities or molecular reservoirs

FEBS Letters
S Khochbin, H Y Kao

Abstract

Recent investigations have allowed the identification of an increasing number of distinct nuclear multi-component complexes containing several types of enzymatic activity. Many of the complexes containing histone deacetylases are believed to control transcription and chromatin remodeling. We suggest here that at least some of these abundant complexes are likely to be "molecular reservoirs" of dynamic composition that exchange factors with other less abundant and functional complexes, according to specific required activities.

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Citations

Sep 6, 2011·Functional & Integrative Genomics·Ehsan HabibiStephen J Haggarty
Sep 16, 2003·Molecular and Cellular Biology·Bernd SchuettengruberChristian Seiser
Jan 25, 2006·Proceedings of the National Academy of Sciences of the United States of America·M V SimoniniA Guidotti
Aug 18, 2004·Biochemical Pharmacology·Vincent Quivy, Carine Van Lint
Jan 25, 2003·Journal of Biochemistry and Molecular Biology·Dong Hoon KimHo Jeong Kwon
Jan 25, 2003·Journal of Biochemistry and Molecular Biology·Roger W L GodschalkHelmut Bartsch
Aug 12, 2008·Biochimica Et Biophysica Acta·Annamaria ScognamiglioLucia Altucci
Aug 5, 2003·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Frédéric CatezMichael Bustin
Jan 10, 2002·The Journal of Biological Chemistry·Wen-Ming YangEdward Seto
Jun 26, 2002·The Journal of Biological Chemistry·Shih-Chang Tsai, Edward Seto
Feb 19, 2003·The Journal of Biological Chemistry·Kevin PetrieArthur Zelent
Aug 16, 2003·The Journal of Biological Chemistry·Ya-Li Yao, Wen-Ming Yang
Oct 26, 2001·The Journal of Biological Chemistry·Hung-Ying KaoRonald M Evans
May 29, 2004·The Journal of Biological Chemistry·Xiaofang LiHung-Ying Kao

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