Histone mediated gene activation in Toxoplasma gondii

Molecular and Biochemical Parasitology
William J Sullivan, Mohamed-Ali Hakimi

Abstract

DNA processes, including transcriptional activation, are largely governed by histone modifications. For most eukaryotes, chromatin-remodeling machines have been identified that move, replace, or decorate histones. Recent studies have shed some important light on similar machinery operating in apicomplexan parasites, including the opportunistic pathogen Toxoplasma gondii. Here we present a synthesis of the current knowledge of histone mediated gene expression in Toxoplasma, particularly in the context of parasite differentiation.

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Citations

Jun 2, 2010·Parasitology Research·Sini SkariahDana G Mordue
Apr 8, 2009·The Journal of Experimental Medicine·Alexandre BougdourMohamed-Ali Hakimi
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Aug 3, 2021·Antimicrobial Agents and Chemotherapy·Marjan EnshaeiehMohammad Sayyah

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