PMID: 108377Apr 1, 1979

Histopathologic and bacterial evaluation of conventional and new copper amalgams

Journal of Oral Pathology
HeysJ K Avery


In vivo pulpal responses in monkeys and in vitro bacterial inhibition studies were completed on new copper amalgams, Sybraloy, Dispersalloy, Tytin and a conventional Spheraloy amalgam. Amalgams were placed in cavities lined with ZOE and in unlined cavities. Silicate and ZOE were used as controls. A total of 165 adult monkey teeth were evaluated at 3 days, 5 and 8 weeks. At 3 days the pulpal responses elicited by the copper amalgams appeared similar to conventional Spheraloy, all showing a slight to moderate response. At 5 weeks the majority of amalgams exhibited a slight pulpar response with a tubular reparative dentin under each restoration. The 8 week pulpal response showed a reduction of the inflammatory response characterized by a tubular reparative dentin with a uniform zone of predentin. Lined ZOE controls exhibited a slight response while silicate showed a moderate response with some persistent chronic inflammation. In vitro bacterial tests revealed that the various amalgams had little to no inhibitory effect on the three serotypes of S. mutans that are most prominent in humans.


Nov 1, 1977·Scandinavian Journal of Dental Research·S Espevik
Mar 1, 1977·Journal of Dental Research·W J LoescheM P Woolfolk
Jan 1, 1974·Scandinavian Journal of Dental Research·J Leirskar
Jun 1, 1972·The Journal of the American Dental Association·G C Paffenbarger
Jul 1, 1972·Oral Surgery, Oral Medicine, and Oral Pathology·I A Mjör, L Tronstad
Jul 1, 1967·The Journal of the American Dental Association·H R StanleyM G Buonocore
Dec 1, 1955·Oral Surgery, Oral Medicine, and Oral Pathology·V E JAMES, I SCHOUR
Feb 1, 1956·Journal of Dental Research·D E SHAYR F MANTZ
Nov 1, 1959·The Journal of the American Dental Association·D F MITCHELL
Sep 1, 1951·Oral Surgery, Oral Medicine, and Oral Pathology·R W McCUED E SHAY


Sep 1, 1989·Dental Materials : Official Publication of the Academy of Dental Materials·J J MorrierJ Dumont
Sep 1, 1981·Journal of Dentistry·D BrownH J Wilson
Apr 1, 1981·Journal of Oral Pathology·C T HanksR G Craig
Sep 1, 1982·Journal of Oral Rehabilitation·P M Dummer, K A Harrison
Nov 1, 1984·Journal of Oral Rehabilitation·P M Dummer, M Wills-Wood
Jan 1, 1987·International Endodontic Journal·R S TobiasR M Browne
Jul 1, 1994·The Journal of the American Dental Association·C F Cox, S Suzuki

Related Concepts

Dental Amalgam
Dental Pulp
Dentin, Secondary
Macaca mulatta
Streptococcus mutans

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