PMID: 999143Nov 1, 1976Paper

Histopathologic and experimental models for sensory and neural deafness

The Annals of Otology, Rhinology, and Laryngology
G J Spector


Six selected cases with neonatal and fetal cochlear pathology are presented. Those denoting cochlear sepsis are: H. influenza purulent labyrinthitis, cytomegalovirus endolabyrinthitis, and aseptic meningitis and labyrinthitis. Those denoting cochlear neural aplasia are Goldenhar's syndrome, left-sided cardiac hypoplasia with partial basal turn neural aplasia, and cerebral cortical and ventricular hemorrhage with modiolar extension. These findings are compared to the fluorocitrate ototoxicity model for neural deafness in the guinea pig. This study suggests hypotheses for viral trophism in the inner ear and neural degeneration of the cochlea as mechanisms for sensorineural deafness.


Apr 1, 1975·Infection and Immunity·R C KaneW L Bayer
Mar 1, 1976·The Annals of Otology, Rhinology, and Laryngology·G J Spector, C D Carr
Mar 27, 1975·Nature·L E DavisR T Johnson
May 1, 1969·American Journal of Diseases of Children·G H McCrackenH F Eichenwald
Nov 1, 1968·The Laryngoscope·E N Myers, S Stool
Dec 1, 1969·The Annals of Otology, Rhinology, and Laryngology·G L Davis
Jul 5, 1973·The New England Journal of Medicine·D W ReynoldsC A Alford
Jul 1, 1973·The Annals of Otology, Rhinology, and Laryngology·G L Davis, M Strauss
Aug 1, 1974·The Journal of Speech and Hearing Disorders·A J DahleS Stagno
Oct 1, 1974·American Journal of Diseases of Children·A S Yeager
Oct 1, 1974·The Laryngoscope·G J Spector, F E Lucente
Jan 1, 1973·The Journal of Pediatrics·W Lindsay
Mar 1, 1973·American Journal of Diseases of Children·S S Budden, G C Robinson
Jan 1, 1967·Archives of Otolaryngology·C A Proctor, B Proctor
Apr 1, 1971·The Annals of Otology, Rhinology, and Laryngology·R Gacek
Dec 1, 1960·The Journal of Laryngology and Otology·F C ORMEROD
Sep 1, 1960·Acta Oto-laryngologica·B MARTENSSON
Sep 1, 1962·The Laryngoscope·H F SCHUKNECHTL RUEDI
Apr 1, 1962·The Laryngoscope·P H WARDJ R LINDSAY
Nov 1, 1963·The Journal of Pediatrics·R J GORLINE GOLDSCHMIDT
Aug 1, 1964·Developmental Medicine and Child Neurology·R W SMITHELLS
Dec 1, 1950·The Annals of Otology, Rhinology, and Laryngology·C E KINNEY

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Oct 1, 1985·Journal of Communication Disorders·P Belenchia, P McCardle
Oct 20, 2001·The Annals of Otology, Rhinology, and Laryngology·M MiuraB E Hirsch
Jul 1, 1986·The Annals of Otology, Rhinology, and Laryngology·I Sando, M Ikeda
Jul 13, 2001·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·A W ScholtzA Schrott-Fischer
Jul 1, 1984·The Annals of Otology, Rhinology & Laryngology. Supplement·G J Spector

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