Histopathological and immunohistochemical findings in lymphoid tissues of the endangered Iberian lynx (Lynx pardinus).

Comparative Immunology, Microbiology and Infectious Diseases
Laura PeñaBelén Sánchez

Abstract

The Iberian lynx (Lynx pardinus) is the most threatened wild feline in the world. Little is known about the diseases and pathology that affect this animal. The aim of this study was to evaluate the histopathological status of the peripheral lymphoid tissues and thymus of Iberian lynxes necropsied between 1998 and 2003. Seventeen animals including females (n=8) and males (n=9), age range of 10 months to 16 years, with different causes of death were histopathologically and immunohistochemically (anti-CD3, CD79, MAC387, CD68) studied. Feline immunosuppressive virus laboratorial tests were negative. Five individuals presented neoplasia and/or tuberculosis. All animals presented some degree of both B and T cells depletion in peripheral lymphoid tissues and follicular hyalinosis in the center of depleted follicles. A viral origin of the lymphoid depletion is postulated although other causes (inbreeding, stress, toxic) are not ruled out. The loss of the effectiveness of the immune system increases the vulnerability of the critically endangered Iberian lynx to pathogens.

References

Nov 17, 1998·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·M ChristgauR N D'Souza
Apr 11, 2000·Emerging Infectious Diseases·V BrionesL Domìnguez
May 1, 2001·The Veterinary Record·J PérezE Mozos
Feb 6, 2004·The Journal of Heredity·W E JohnsonS J O'Brien
Jun 9, 2004·Journal of Clinical Microbiology·Alicia AranazLucas Domínguez

❮ Previous
Next ❯

Citations

Apr 21, 2012·Animal Reproduction Science·Sirirak BuarpungMongkol Techakumphu
Mar 29, 2011·Veterinary Microbiology·Christian GortazarJosé de la Fuente
Nov 10, 2009·Veterinary Immunology and Immunopathology·Marina L MeliHans Lutz
Dec 17, 2008·The Veterinary Journal·Ignacio GarcíaFernando Martínez
Jun 17, 2008·The Veterinary Journal·Javier MillánLuis León-Vizcaíno
Sep 8, 2010·Integrated Environmental Assessment and Management·Jin ZhouXiao-Shan Zhu
Oct 17, 2013·Molecular Ecology·M Casas-MarceJ A Godoy
May 8, 2008·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Inés LuacesEsperanza Gómez-Lucía
Apr 7, 2019·Heredity·Daniel Kleinman-RuizJosé A Godoy
Jan 1, 2008·European Journal of Wildlife Research·Melody E RoelkeStephen J O'Brien
Apr 9, 2021·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Alison E StoutGary R Whittaker

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Related Concepts

Related Feeds

B-Cell Leukemia (Keystone)

B-cell leukemia includes various types of lymphoid leukemia that affect B cells. Here is the latest research on B-cell leukemia.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.