Histopathological changes in the liver and stomach of Didelphis virginiana (Didelphimorphia: Didelphidae) during natural infection with Gnathostoma turgidum (Nematoda: Gnathostomidae)

Journal of Helminthology
Edith Hilario Torres-MontoyaJose Rendon-Maldonado

Abstract

Gnathostoma turgidum is a nematode parasite that exploits the stomach of Virginian opossums, Didelphis virginiana, in Latin America. The opossum is the definitive host of G. turgidum in the wild. Intrahepatic growth and maturation of the parasite, subsequent migration to the stomach and spontaneous expulsion are common. However, the histopathological lesions caused by G. turgidum are poorly described. A better understanding of the life cycle of this parasite and the pathological changes in natural host-parasite interactions could help to clarify the progression of human infections caused by Gnathostoma binucleatum. The aim of this work was to study morphological changes in the liver and stomach of D. virginiana during natural infection and adult worm expulsion. Three opossums naturally infected with G. turgidum were captured from an endemic area of gnathostomosis. Three uninfected opossums captured from a non-endemic area were used as controls. The opossums were sacrificed at different stages of infection (March, May and December), and a histopathological study of their livers and stomachs was conducted. Injuries in livers were observed by histopathology - areas of necrosis and collagen septa were identified. Parasites caused n...Continue Reading

References

Oct 26, 2007·Journal of Helminthology·Luis A MarcosAngélica Terashima
May 13, 2008·Gastroenterology·Scott L Friedman
Nov 8, 2008·The Journal of Parasitology·Sylvia Páz Díaz-CamachoYukifumi Nawa
Mar 24, 2010·The Journal of Hospital Infection·R LinertováP Serrano-Aguilar
Feb 11, 2014·Journal of Wildlife Diseases·Hilario Torres-MontoyaJose Rendon-Maldonado

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Citations

Apr 1, 2021·Parasitology Research·Marcos Antônio Bezerra-SantosDomenico Otranto

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