PMID: 591989Dec 1, 1977

Histopathological variability in 'standardised' spinal cord trauma

Journal of Neurology, Neurosurgery, and Psychiatry
G Koenig, G J Dohrmann

Abstract

Feline spinal cords were traumatised by the weight dropping technique. Five trauma groups were studied (5 g X 80 cm, 10 g X 40 cm, 20 g X 20 cm, 40 g X 10 cm, and 80 g X 5 cm), each having a 'standardised' injury of '400 g--cm.' The spinal cords were sectioned serially two hours after contusion and examined by light microscopy. Relative to the larger weights falling from lesser heights, the smaller weights falling from greater heights were associated with less haemorrhage, oedema, axonal disruption, and myelin fragmentation as well as a smaller volume of grey matter containing altered anterior horn cells. In all trauma groups the cortical evoked responses disappeared at the time of the injury and did not reappear. Even though each trauma group received a '400 g--cm' contusion, each weight--height combination was associated with differing degrees of histopathological alterations. A plea is made for more accurate quantitation of experimental spinal cord trauma than the 'g--cm' unit.

References

Feb 1, 1975·Paraplegia·J D YeoA D Kidman
Mar 1, 1973·Journal of Neurosurgery·C M D'AngeloA Taub
Dec 1, 1972·Archives of Neurology·G J Dohrmann
Dec 1, 1971·Journal of Neurosurgery·T B DuckerL G Kempf
Jan 1, 1970·Brain : a Journal of Neurology·S NurickM D Deck
Aug 1, 1971·Journal of Neurosurgery·I M Turnbull
Sep 1, 1971·Journal of Neurosurgery·F C WagnerP C Bucy
Sep 1, 1971·Journal of Neurosurgery·D J Fairholm, I M Turnbull

Citations

Jul 17, 2008·Journal of Neurotrauma·Jason T MaikosDavid I Shreiber
Dec 1, 1980·Journal of Neurosurgery·E J DolanL Endrenyi
Aug 1, 1983·Journal of Neurosurgery·R W Ford
Aug 1, 1985·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·M KhanM Politis
Jul 1, 1988·The Journal of the American Paraplegia Society·C H Sutton

Related Concepts

Metazoa
Anterior Horn Cells
Axon
Felis catus
Contusions
Potentials, Event-Related
Study, Methodological
Myelin
Somatosensory Cortex
Spinal Cord

Related Feeds

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.