PMID: 11920512Mar 29, 2002Paper

Histopathology and MIB-1 labeling index predicted recurrence of meningiomas: a proposal of diagnostic criteria for patients with atypical meningioma

Cancer
Donald Ming-Tak HoHung Chiang

Abstract

Although various histopathologic features have been associated with aggressive behavior or recurrence of meningiomas, there is little agreement about which features are the most important and in what combination. The objective of this study was to formulate diagnostic criteria for atypical meningioma. Eighty-three patients with meningiomas who underwent macroscopic total resection and had been followed until they developed recurrent disease or for at least 10 years were studied. Thirteen histopathologic parameters that related to recurrence of the tumor were evaluated in each patient. All possible combinations of histologic parameters that were related significantly to recurrence were used to formulate scoring models. The model that included the fewest parameters and that could distinguish tumor recurrence best within 10 years was chosen as the final model. The final model included three parameters: loss of architecture, mitoses > or= 1.5/mm2, and necrosis. Of the 52 tumors with a score < 2 (0 or 1 of the 3 parameters), all except 1 tumor did not recur within 10 years, and they were all considered benign meningiomas. Of the 31 tumors with a score > or = 2 (2 or 3 of the 3 parameters), 94% recurred within 10 years (76% recurred ...Continue Reading

References

Dec 1, 1986·The American Journal of Surgical Pathology·S M de la MonteR M Linggood
Mar 1, 1986·Surgical Neurology·J JääskeläinenA Servo
Jan 1, 1985·Journal of Neurosurgery·R O MirimanoffR L Martuza
May 1, 1985·Journal of Neurosurgery·D C MillerH C Grillo
Jan 15, 1983·International Journal of Cancer. Journal International Du Cancer·J GerdesH Stein
Mar 22, 1994·Proceedings. Biological Sciences·M D Baker, J M Ritchie
Jul 1, 1993·European Journal of Cancer. Part B, Oral Oncology·I R KramerM Shear
Sep 1, 1997·Journal of Neuro-oncology·M L Møller, O Braendstrup
Dec 31, 1997·The American Journal of Surgical Pathology·A PerryC M Lohse
Mar 7, 1998·Human Pathology·E KaramitopoulouA Probst
May 12, 1998·Journal of Neurosurgery·B J McCarthyE R Laws
Oct 6, 1998·Journal of Neuro-oncology·C C CokeW J Curran
Mar 11, 1999·Acta neurochirurgica·G NagashimaK Hirakawa
Mar 21, 2001·The American Journal of Surgical Pathology·S NakasuM Matsuda
Jun 1, 1997·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·M HummelP Fürst

❮ Previous
Next ❯

Citations

Jul 20, 2006·Acta Neuropathologica·V BarresiG Barresi
Apr 9, 2008·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Yoshiharu KawaguchiTomoatsu Kimura
Oct 27, 2009·Brain Tumor Pathology·Satoshi NakasuKazuhiko Nozaki
Sep 6, 2006·Neurosurgical Review·Hidetoshi KasuyaTomokatsu Hori
May 27, 2011·Neurosurgical Review·Chien-Min ChenYong-Kwang Tu
Jul 3, 2013·Journal of Neuro-oncology·Wen-Chiuan TsaiDueng-Yuan Hueng
Apr 15, 2003·Current Neurology and Neuroscience Reports·Anthony L D'Ambrosio, Jeffrey N Bruce
Nov 21, 2007·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Mahesha VankalakuntiVirender Kumar Khosla
Sep 25, 2008·Neurosurgery·Andrew P MorokoffPeter M Black
Aug 22, 2008·Neurosurgery·Peter M BlackJacob Zauberman
Oct 27, 2011·The Oncologist·Santosh SarafJ Lee Villano
Jun 24, 2005·Neurologia Medico-chirurgica·Masaru HondaIzumi Nagata
Aug 4, 2009·Journal of Neurosurgery·Nader SanaiMichael W McDermott
Oct 27, 2007·Neurosurgical Focus·Jason RockhillMarc C Chamberlain
Oct 27, 2007·Neurosurgical Focus·Deborah L ComminsMargaret E Burnett
Oct 27, 2007·Neurosurgical Focus·Leland Rogers, Minesh Mehta
Jan 27, 2005·Neurosurgical Focus·Stephen J Hentschel, Franco DeMonte
Jun 5, 2007·Journal of Neurosurgery·Carlos A MattozoMichael T Selch
Dec 24, 2005·Journal of Neurosurgery. Spine·Patrick CramerChristian Woiciechowsky
Apr 13, 2011·Neurology India·Sashidhar BabuSundaram Challa
Nov 16, 2013·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·David S BaxterTiit Mathiesen
Jun 25, 2013·Brain Tumor Pathology·Ata Türker ArikökMurat Alper
Jan 18, 2007·Journal of Neuro-oncology·Francesco MaiuriEnrico de Divitiis
Mar 26, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Mirco BartolomeiGiovanni Paganelli
Apr 4, 2014·Neuro-oncology·Gurvinder KaurAndrew T Parsa
Oct 14, 2005·Expert Review of Anticancer Therapy·Douglas Strother
Nov 21, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Arash NayeriLola B Chambless
Jul 23, 2013·World Neurosurgery·Ahmed ZaherSylvia A Ashamallah
Jan 31, 2012·Clinical Neurology and Neurosurgery·Marko AndricAndrew Hunn
Jan 19, 2012·World Neurosurgery·Jenny Pettersson-SegerlindTiit Mathiesen
Jan 14, 2011·Clinical Neurology and Neurosurgery·George A AlexiouAthanasios P Kyritsis
Oct 19, 2010·Pathology, Research and Practice·Ellen AbrySverre H Torp
Sep 28, 2015·Journal of Neuro-oncology·Winward ChoyOrin Bloch
Jun 21, 2007·American Journal of Clinical Pathology·Yoo-Jin KimWolfgang Feiden
Feb 26, 2008·International Journal of Radiation Oncology, Biology, Physics·David PasquierUNKNOWN Rare Cancer Network
May 15, 2007·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Kwang-Won KoJong-Hyun Kim
Jan 24, 2007·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Angela AlamaJean Louis Ravetti
Nov 7, 2006·Neuropathology and Applied Neurobiology·S LongL Nasir
Apr 27, 2013·Histopathology·Xiao-Qiang WangCheng-Chuan Jiang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.