Historical note: the extraordinary handless and footless families of Brazil - 50 years of acheiropodia

American Journal of Medical Genetics
A Freire-Maia

Abstract

The history of acheiropodia is divided into 4 phases: discovery, exploration, modern studies, and contemporary knowledge. The discovery phase (1929-1930) is represented by the publication of the 1st family. For about 30 years, it remained the only family referred to in a number of textbooks of medicine, biology, and others. In the exploration phase (1956-1966), the first family was reanalyzed, other families were ascertained and analysed, and some radiologic aspects of the anomaly were published. The modern phase (1968-1972) is characterized by a large series of studies on the clinical aspects of acheiropodia, including laboratory and radiological examinations, psychological tests, status of vision, electrocardiograms, etc. In the contemporary phase (since 1974), genetic aspects prevailed, and studies were published on segregation analysis, selection pressure, genetic load, mutation rate, etc. Each one of these 4 phases is analyzed in detail.

References

Jan 1, 1978·American Journal of Medical Genetics·A Freire-MaiaN Freire-Maia
Jan 1, 1979·American Journal of Medical Genetics·F A MarçalloA Freire-Maia
Jan 1, 1977·Acta geneticae medicae et gemellologiae·P A MourãoC P Dietrich
Mar 7, 1970·Lancet·A Freire-Maia
May 30, 1970·Lancet·G R Fraser
Oct 3, 1970·Lancet·A Freire-Maia

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Citations

Jul 1, 1990·American Journal of Medical Genetics·A C Fett-Conte, A Richieri-Costa
May 9, 2012·Journal of Community Genetics·Dafne Dain Gandelman HorovitzAntonia Paula Marques-de-Faria
Mar 25, 2009·Journal of Children's Orthopaedics·Ismat Ghanem
Jan 1, 1981·American Journal of Medical Genetics·O Frota-Pessoa
Oct 1, 1994·American Journal of Medical Genetics·T Anderson
Dec 1, 1983·American Journal of Medical Genetics·A GrimaldiA Freire-Maia
Jun 1, 1985·Journal of American College Health : J of ACH·N R Hester, D M Macrina
Oct 27, 1998·Clinical Genetics·E L Silveira, A Freire-Maia
Apr 26, 2014·Genetics and Molecular Biology·Eduardo E Castilla, Lavinia Schuler-Faccini
Oct 1, 1994·The Journal of Bone and Joint Surgery. American Volume·L M Kruger, A Kumar

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