PMID: 11926753Apr 3, 2002Paper

Historical overview of the use of cytomegalovirus hyperimmune globulin in organ transplantation

Transplant Infectious Disease : an Official Journal of the Transplantation Society
David R Snydman

Abstract

A historical review of the development of cytomegalovirus hyperimmune globulin (CMV-IG, CytoGam) shows its increasing use in solid organ transplant (SOT) recipients, either alone or in combination with ganciclovir. A review of clinical trials of CytoGam in renal transplant recipients shows reductions in CMV-associated syndromes and fungal and parasitic superinfections, and increases in graft survival, while CytoGam prophylaxis trials in orthotopic liver transplant (OLT) recipients have produced reductions in severe CMV-associated disease and invasive fungal disease. A combination of CytoGam plus ganciclovir in OLT recipients has resulted in reductions in CMV hepatitis and infection, and CMV disease and viremia, plus a trend in improved 1- and 2-year survival rates.

References

Jan 1, 1979·Seminars in Thrombosis and Hemostasis·J S Finlayson
Oct 22, 1987·The New England Journal of Medicine·D R SnydmanA S Levey
Jul 1, 1982·The Journal of Infectious Diseases·J AbbG G Jackson
Feb 1, 1981·The Journal of Pediatrics·A S YeagerC G Prober
Apr 1, 1981·The Journal of Infectious Diseases·J E Osborn
Sep 7, 1995·The New England Journal of Medicine·H A Valantine, J S Schroeder
Nov 15, 1993·Annals of Internal Medicine·D R SnydmanUNKNOWN Boston Center for Liver Transplantation CMVIG Study Group
Jun 7, 2007·Neurorehabilitation and Neural Repair·Hans-Otto Karnath, Doris Brötz

❮ Previous
Next ❯

Citations

Jun 19, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Stanley A Plotkin
Jul 26, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Gilberto Torres-Madriz, Helen W Boucher
Jun 29, 2006·Inflammatory Bowel Diseases·Dustin G JamesWilliam F Stenson
Oct 10, 2008·Journal of Virology·Durdica CekinovićStipan Jonjić
May 17, 2011·Pharmacology & Therapeutics·Beatrice MercorelliArianna Loregian
Dec 10, 2015·Bioanalysis·Yan J ZhangDharmesh D Desai
Nov 3, 2005·Clinics in Chest Medicine·Michael G Ison, Jay A Fishman
Jun 21, 2008·The British Journal of Dermatology·A PollreiszH J Ankersmit
Jul 15, 2004·International Immunopharmacology·Matthias BudtHartmut Hengel
Jan 18, 2005·Antiviral Research·David L EversEng-Shang Huang
Apr 1, 2015·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Misako YajimaKimiyasu Shiraki
Dec 30, 2014·Cellular & Molecular Immunology·A Louise McCormick, Edward S Mocarski
Jun 6, 2003·Journal of the American College of Surgeons·Andrew W KirkpatrickDavid L Dawson
Jun 10, 2017·Viral Immunology·Nobuyasu AibaKimiyasu Shiraki
Dec 24, 2014·Antimicrobial Agents and Chemotherapy·Lawrence M KauvarLenore Pereira
Nov 18, 2003·Transplant Infectious Disease : an Official Journal of the Transplantation Society·E F de MaarW J van Son
Mar 2, 2013·The Cochrane Database of Systematic Reviews·Elisabeth M HodsonJonathan C Craig

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.