History-dependent force, angular velocity and muscular endurance in ACTN3 genotypes

European Journal of Applied Physiology
Siacia BroosMartine A Thomis

Abstract

This study aimed at determining the influence of the ACTN3 R577X polymorphism on muscle strength and muscle endurance in non-athletic young men. 266 healthy young men were included in this study. Each subject performed maximal isometric, concentric and eccentric contractions of the knee extensor muscles on an isokinetic dynamometer. Force depression, force enhancement and the fatigue index were derived from these data. In addition, handgrip strength, squat jump (SJ) and counter movement jump (CMJ) height were obtained. Our group included 83 RR (31 %), 131 RX (49 %) and 52 XX (20 %) individuals. The muscle bone cross-sectional area of the thigh was 5 % higher in RR compared to XX individuals (P = 0.033). RR genotypes showed 6 % higher handgrip strength compared to the XX group (P = 0.047). They also jumped 5 % higher in both the SJ and CMJ tests (P = 0.029; P = 0.031). No differences were found in force depression, force enhancement, isometric or eccentric strength. The relative concentric knee torque at 200°/s and at 300°/s was 7 and 8 % higher in RR compared to XX genotypes, respectively (P = 0.049; P = 0.048). Also, the fatigue index was found to be 4 % lower in XX genotypes (P = 0.037). Our findings are in agreement with the...Continue Reading

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Citations

Feb 27, 2016·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Shinsuke NirengiNaoki Sakane
Mar 2, 2016·PloS One·Siacia BroosMarc Francaux
May 18, 2016·Medicine and Science in Sports and Exercise·Mark A SarzynskiClaude Bouchard
Oct 3, 2015·Medicine and Science in Sports and Exercise·Fleur C Garton, Kathryn N North
Jan 10, 2020·Journal of Strength and Conditioning Research·Victor Moreno-PérezJuan Del Coso
Nov 2, 2019·Journal of Human Kinetics·Daria Domańska-SenderowskaEwa Brzeziańska-Lasota
Sep 24, 2015·Physiological Genomics·Fleur C GartonAlejandro Lucia
Oct 18, 2018·European Journal of Applied Physiology·Juan Del CosoAlejandro Lucía
Sep 11, 2018·Journal of Strength and Conditioning Research·John P WagleMichael H Stone
Jun 2, 2021·Journal of Sport and Health Science·Daiani de CamposHeiliane de Brito Fontana

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