PMID: 6965817Apr 1, 1980Paper

History of nightblindness: a simple tool for xerophthalmia screening

The American Journal of Clinical Nutrition
A SommerJ S Saroso

Abstract

Among 5925 preschool-age children examined in a house to house rural field study, X1B (Bitot's spot with xerosis) and/or an history of nightblindness (XN) was presented in 325. Mean serum vitamin A levels among those with isolated XN (13.9 microgram/dl), isolated X1B (13.4 micrograms/dl), and coexistent XN/X1B (12.1 microgram/dl) were similar, and significantly below that of normal age/sex/neighborhood matched controls (17.6, 17.1, and 18.3 microgram/dl, respectively). The mean serum vitamin A level of the matched controls was significantly below that of normal, randomly sampled children from the study population as a whole (20.6 microgarm/dl). As independent screening criteria, disregarding the presence of absence of other signs, twice as many children had a history of XN as had X1B (84 and 41% of all clinically abnormal children, respectively). Of randomly sampled children 55% but only 15% of cases of XN had serum vitamin A levels above 20 microgram/dl. Of children with a history of nightblindness 97% had impaired scotopic vision on objective testing, but the mean serum vitamin A levels among test positives and negatives were identical. These results suggest a properly eleicited history of nightblindness can be almost as spec...Continue Reading

Citations

Jul 1, 1988·JPEN. Journal of Parenteral and Enteral Nutrition·M M GottschlichJ W Alexander
Jul 1, 1984·The British Journal of Nutrition·M U KhanM R Khan
Nov 8, 2011·Ophthalmic Epidemiology·Garry BrianCamilla Gould
Feb 14, 2012·Transactions of the Royal Society of Tropical Medicine and Hygiene·Justin C SherwinJeremiah Ngondi
Jan 1, 1990·Annals of the New York Academy of Sciences·A Sommer
Aug 1, 1992·Australian and New Zealand Journal of Ophthalmology·J DanksJ Rait
Jan 1, 1983·The Proceedings of the Nutrition Society·A Pirie
Feb 1, 1996·Tropical Medicine & International Health : TM & IH·A Hussain, G Kvále
Oct 23, 2004·Eye & Contact Lens·Lisa D MihoraRobert W Enzenauer
Jul 19, 2006·Nutrition Journal·Augustin N ZebaHélène F Delisle
Nov 21, 2019·Nutrición hospitalaria·Sílvia PereiraAndréa Ramalho
Jan 1, 1989·Journal of the Royal Society of Medicine·S A VernonE J Hiller
Feb 1, 1990·The British Journal of Ophthalmology·R Loewenthal, J Pe'er
Nov 1, 1992·International Ophthalmology·S ResnikoffO Amedee-Manesme
Feb 1, 1994·Nutrition Reviews·A Sommer
Dec 4, 2003·European Journal of Clinical Nutrition·R D SembaM W Bloem
Oct 5, 2006·Food and Nutrition Bulletin·Keith P West
Apr 30, 2016·Critical Reviews in Food Science and Nutrition·Elina Manusevich WisemanRam Reifen
Sep 11, 2002·The Journal of Nutrition·Nathan G Congdon, Keith P West
Apr 16, 1998·Progress in Retinal and Eye Research·A Sommer

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