PMID: 22335847Feb 18, 2012Paper

History of the use of immunoglobulin

Zhonghua yi shi za zhi = Chinese journal of medical history
Ning XiangWen-Li Hu

Abstract

In 1890, the German scholar Von Behring found animal serum antitoxin. In 1940, Cenci advocated to use recovery-stage patients' serum instead of animal serum for its anaphylactic reaction. In 1973, Tiselius separated immunoglobulin from serum with electrophoresis techniques. In 1940, immunoglobulin's preparation process was published by Cohn and his colleagues. After the Second World War, immunoglobulin was used by civilians for prevention and treatment of infectious diseases. Bruton found the lack of γ-globulins in primary immunodeficiency patients in 1952, and immunoglobulin was used to treat this disease. From then on, immunoglobulin began to be used for immunodeficiency disease. In 1981, Imbach achieved success in idiopathic thrombocytopenic purpura with immunoglobulin. Immunoglobulin came into use for autoimmune disease subsequent to that.

Related Concepts

Related Feeds

Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Transfusion clinique et biologique : journal de la Société française de transfusion sanguine
J BayryS V Kaveri
Nihon rinsho. Japanese journal of clinical medicine
Masako Hara
© 2022 Meta ULC. All rights reserved