Hitting HIV's Harpoon

Immunity
Marit J van Gils, Rogier W Sanders

Abstract

The HIV-1 fusion peptide is a target for broadly neutralizing antibodies. In a recent issue of Nature Medicine, Xu et al. (2018) provide proof-of-concept that vaccination with fusion peptide followed by vaccination with an envelope glycoprotein trimer can induce antibodies in animal models that neutralize diverse HIV-1 viruses.

Citations

Jan 31, 2019·The Journal of Biological Chemistry·Dirk EgginkRogier W Sanders
Nov 28, 2018·Retrovirology·Jelle van Schooten, Marit J van Gils

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