PMID: 16618008Apr 19, 2006Paper

"Hitting" voices of schizophrenia patients may lastingly reduce persistent auditory hallucinations and their burden: 18-month outcome of a randomized controlled trial

Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie
Jack A JennerDurk Wiersma

Abstract

This study aimed to investigate the outcome of an 18-month randomized controlled trial (RCT) on subjective burden and psychopathology of patients suffering from schizophrenia. An RCT was used to compare hallucination-focused integrative treatment (HIT) and routine treatment (RT) in schizophrenia patients who persistently hear voices. We performed an intent-to-treat analysis on each of the 63 patients who were assessed at baseline, 9, and 18 months. On each of the 3 occasions, the differential effects of the treatment conditions were tested repeatedly. Sex, age, education, and illness (hallucination) duration were used as covariates. Patients in the experimental group retained improvements over time. Improvements in hallucinations, distress, and negative content of voices remained significant at the 5% level. HIT seems to be an effective treatment strategy with long-lasting effects for treatment-refractory voice-hearing patients.

References

Feb 1, 1995·Schizophrenia Research·J P LindenmayerR B Hyman
Feb 10, 1996·BMJ : British Medical Journal·R KempA David
Nov 1, 1996·The British Journal of Psychiatry : the Journal of Mental Science·V DruryF Macmillan
Nov 28, 1997·The British Journal of Psychiatry : the Journal of Mental Science·E KuipersC Hadley
Oct 21, 2000·The British Journal of Psychiatry : the Journal of Mental Science·P ChandwickM Birchwood
Feb 7, 2001·The American Journal of Psychiatry·J BustilloS Keith
Apr 11, 2001·Schizophrenia Research·R A GouldD Goff
Jul 4, 2002·Psychiatric Services : a Journal of the American Psychiatric Association·Jack A Jenner
May 6, 2003·Journal of Marital and Family Therapy·William R McFarlaneAlicia Lucksted
Feb 27, 2004·Acta Psychiatrica Scandinavica·D WiersmaG van de Willige
Jun 5, 2004·Schizophrenia Bulletin·Jack A JennerGerard van de Willige
Apr 2, 2005·The British Journal of Psychiatry : the Journal of Mental Science·Lucia R ValmaggiaCees J Slooff

❮ Previous
Next ❯

Citations

Jan 8, 2008·Perspectives in Psychiatric Care·Margaret England
Oct 19, 2007·Acta Psychiatrica Scandinavica·J A Jenner
Mar 29, 2007·Perspectives in Psychiatric Care·Margaret England
Jun 25, 2009·International Journal of Group Psychotherapy·John R SaksaScott W Woods
Mar 1, 2012·Schizophrenia Bulletin·Iris E C SommerMark van der Gaag
May 30, 2013·Journal of Psychiatric and Mental Health Nursing·J K Schnackenberg, C R Martin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.