PMID: 11909740Mar 23, 2002Paper

HIV-1 and the brain: connections between HIV-1-associated dementia, neuropathology and neuroimmunology

Microbes and Infection
Diane M Lawrence, Eugene O Major

Abstract

AIDS patients frequently exhibit neurological disorders due to the neurotoxic events that result from HIV-1 and/or opportunistic infections in the brain. This review examines recent clinical findings related to HIV-1-associated dementia, and outlines current areas of basic research that may clarify how HIV-1-associated encephalopathy produces clinical symptoms of brain dysfunction.

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