HIV and malaria interactions: where do we stand?

Expert Review of Anti-infective Therapy
Raquel GonzálezAlfredo Mayor

Abstract

Reversing the spread of HIV infection and the incidence of malaria constitute two of the Millenium Development Goals. However, despite recent achievements, both diseases still entail global heath problems. Furthermore, their overlapping geographical distribution raises concerns and challenges for potential immunological, clinical and therapeutic interactions. It has been reported that HIV infection increases malaria susceptibility and reduces the efficacy of antimalarial drugs. On the other hand, the effect of malaria on HIV-infected individuals has also been explored, with the parasitic infection increasing the risk of HIV disease progression and mother-to-child transmission of HIV. The spread of malaria and parasite resistance to antimalarials could also be accelerated by HIV-associated immunosuppresion. Current knowledge of the epidemiological, clinical, immunological and therapeutic interactions of the two diseases is reviewed in this article. We focus on the latest available data, pointing out key future research areas and challenges of the field.

References

Jan 1, 1996·The American Journal of Tropical Medicine and Hygiene·R W SteketeeJ G Breman
May 29, 1998·International Journal of Epidemiology·D Chandramohan, B M Greenwood
Mar 10, 2001·The Journal of Infectious Diseases·A N TkachukS R Meshnick
Oct 9, 2001·HIV Clinical Trials·UNKNOWN Panel on Clinical Practices for Treatment of HIV Infection
Dec 12, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Louise KuhnCaroline Tiemessen
Mar 22, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Morten A NielsenLars Hviid
Jul 20, 2002·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Saidi H KapigaWafaie W Fawzi
Nov 26, 2003·The Journal of Infectious Diseases·Ingrid InionMarleen Temmerman
May 4, 2004·The Journal of Infectious Diseases·Christopher D PilcherUNKNOWN Duke-UNC-Emory Acute HIV Consortium
Jun 18, 2004·Emerging Infectious Diseases·John G AyisiBernard L Nahlen
Mar 29, 2005·Proceedings of the National Academy of Sciences of the United States of America·C J DrakeleyE M Riley
Mar 30, 2005·The Journal of Nutrition·Wafaie FawziDavid J Hunter
Apr 6, 2005·The Journal of Infectious Diseases·Maria J WawerThomas C Quinn
Jun 1, 2005·Trends in Parasitology·Renée M NedVenkatachalam Udhayakumar
Jun 28, 2005·Antimicrobial Agents and Chemotherapy·Sunil ParikhPhilip J Rosenthal
Sep 28, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Megan E O'BrienWafaie W Fawzi
Nov 4, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Cheryl CohenHeather Crewe-Brown
Dec 3, 2005·The Journal of Infectious Diseases·Moses R KamyaDiane Havlir
Dec 13, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jonathan MerminJohn P Ekwaru
Feb 16, 2006·The Journal of Infectious Diseases·Miriam K LauferChristopher V Plowe
Jun 17, 2006·The Journal of Infectious Diseases·Indu MalhotraChristopher L King
Sep 9, 2006·The Journal of Infectious Diseases·Jean-Pierre Van GeertruydenUmberto D'Alessandro
Oct 28, 2006·The Lancet Infectious Diseases·Athena P KourtisMarc Bulterys

❮ Previous
Next ❯

Citations

Mar 2, 2013·The Journal of Infectious Diseases·Alfredo MayorChetan E Chitnis
Mar 4, 2014·Malaria Journal·Raquel GonzálezClara Menéndez
May 6, 2014·The Journal of Infectious Diseases·Wina HasangStephen Rogerson
Mar 11, 2016·Journal of Pediatric Neurosciences·Mahmood Dhahir Al-Mendalawi
Dec 29, 2015·Trends in Parasitology·Beatriz GalatasAlfredo Mayor
Jun 2, 2015·Trends in Microbiology·Ruthie B BirgerC Jessica E Metcalf
Jan 9, 2015·Malaria Journal·Jean-Pierre BizimanaStefan Kienberger
Dec 3, 2014·The Lancet Oncology·Daniela C Stefan
Jan 7, 2014·Trends in Parasitology·Ricardo AtaídeStephen J Rogerson
Oct 22, 2015·The New England Journal of Medicine·Alfredo MayorClara Menéndez
May 4, 2016·PLoS Medicine·Raquel GonzálezClara Menéndez
Jan 28, 2015·The American Journal of Tropical Medicine and Hygiene·Cesar VelascoDenise Naniche
Mar 22, 2018·The Cochrane Database of Systematic Reviews·Raquel GonzálezClara Menéndez
Jul 20, 2017·The American Journal of Tropical Medicine and Hygiene·Francisco Espinoza-GómezUriel A López-Lemus
Nov 28, 2018·The Cochrane Database of Systematic Reviews·Raquel GonzálezClara Menéndez
Oct 24, 2018·The American Journal of Tropical Medicine and Hygiene·Leabaneng TaweGiacomo M Paganotti
May 30, 2019·Transactions of the Royal Society of Tropical Medicine and Hygiene·Oriyomi AkinyotuAyodele Arowojolu
Mar 23, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R Matthew ChicoDaniel Chandramohan
Feb 16, 2013·Expert Review of Anti-infective Therapy·Theonest K Mutabingwa, Ishag Adam
Jun 27, 2020·AIDS·Elina LamCharlotte Martin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Related Papers

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
J-P Van Geertruyden
© 2022 Meta ULC. All rights reserved