HIV and risk environment for injecting drug users: the past, present, and future.

Lancet
Steffanie A StrathdeeCatherine A Hankins

Abstract

We systematically reviewed reports about determinants of HIV infection in injecting drug users from 2000 to 2009, classifying findings by type of environmental influence. We then modelled changes in risk environments in regions with severe HIV epidemics associated with injecting drug use. Of 94 studies identified, 25 intentionally examined risk environments. Modelling of HIV epidemics showed substantial heterogeneity in the number of HIV infections that are attributed to injecting drug use and unprotected sex. We estimate that, during 2010-15, HIV prevalence could be reduced by 41% in Odessa (Ukraine), 43% in Karachi (Pakistan), and 30% in Nairobi (Kenya) through a 60% reduction of the unmet need of programmes for opioid substitution, needle exchange, and antiretroviral therapy. Mitigation of patient transition to injecting drugs from non-injecting forms could avert a 98% increase in HIV infections in Karachi; whereas elimination of laws prohibiting opioid substitution with concomitant scale-up could prevent 14% of HIV infections in Nairobi. Optimisation of effectiveness and coverage of interventions is crucial for regions with rapidly growing epidemics. Delineation of environmental risk factors provides a crucial insight into ...Continue Reading

References

Aug 5, 2000·International Journal of STD & AIDS·S PandaR Detels
Aug 3, 2000·International Journal of Epidemiology·P E EstebanezM V Zunzunegui
Oct 19, 2000·Social Science & Medicine·T BarnettV Steshenko
Jan 5, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·L J OuelletE Monterroso
Aug 3, 2002·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Catherine HankinsUNKNOWN SurvUDI Working Group
Feb 7, 2003·Social Science & Medicine·Carl A LatkinSusan Sherman
Jan 7, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Robert E BoothOleg Semerik
Aug 27, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jacqueline M O'ConnellEvan Wood
Apr 28, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Saman ZamaniSeiichi Ichikawa
Jun 1, 2006·Sexually Transmitted Diseases·Peter VickermanCharlotte Watts
Jun 1, 2006·Journal of Urban Health : Bulletin of the New York Academy of Medicine·K M BlankenshipJ E Mantell
Jun 1, 2006·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Scott S SantibanezAlan E Greenberg
Jun 14, 2006·Drug and Alcohol Dependence·Jose L SanchezKenneth C Earhart
Jan 24, 2007·Bulletin of the World Health Organization·Nguyen Anh TuanNigel O'Farrell
Jul 12, 2007·International Journal of STD & AIDS·Asma BokhariInayat Thaver
Jan 8, 2008·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Steffanie A StrathdeeThomas L Patterson
Jan 23, 2008·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Lucy PlattJohn Parry
Mar 15, 2008·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Alan NeaigusRobert C Baxter
Mar 28, 2008·Tropical Medicine & International Health : TM & IH·Li ZhangYiming Shao
Aug 9, 2008·Lancet·Geeta Rao GuptaAjay Mahal
Mar 18, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Faran EmmanuelPaul Sandstrom
Jun 30, 2009·Drug and Alcohol Dependence·Amanda J RondinelliRichard S Garfein
Aug 18, 2009·Addiction·Robert E BoothLarisa Sinitsyna
Jul 24, 2010·Lancet·Ralf JürgensChris Beyrer

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Citations

Oct 21, 2011·AIDS and Behavior·Shira M GoldenbergSteffanie A Strathdee
Mar 16, 2011·AIDS and Behavior·Glenn-Milo SantosGrant Nash Colfax
Jul 6, 2011·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Alexander BrackChristoph Stein
Jun 8, 2012·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Aleksandar StulhoferAsad Ramlawi
Jul 19, 2012·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Leo BeletskySteffanie A Strathdee
Jul 12, 2012·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Aleksandar StulhoferAsad Ramlawi
Mar 1, 2013·Current HIV/AIDS Reports·Zunyou WuRoger Detels
Apr 13, 2013·Current HIV/AIDS Reports·Catherine Hankins
Jul 31, 2013·Drug and Alcohol Dependence·Leo BeletskyMarina Smelyanskaya
Aug 3, 2013·Drug and Alcohol Dependence·Andrea L WirtzChris Beyrer
Aug 17, 2012·Journal of Public Health Policy·Ernest Drucker
Jul 23, 2011·Medical Anthropology·James QuesadaPhilippe Bourgois
Oct 6, 2011·Global Public Health·Jessica OgdenWilliam F Fisher
Aug 4, 2012·AIDS Research and Human Retroviruses·Saida OsmanRaphael M Lwembe
Feb 2, 2011·The Journal of Infectious Diseases·Jason Grebely, Gregory J Dore
Apr 18, 2013·The Journal of Infectious Diseases·Sarah LarneyJosiah D Rich
Jul 23, 2013·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Sanghyuk S ShinSteffanie A Strathdee
Apr 14, 2012·Current Opinion in HIV and AIDS·Steffanie A StrathdeeUNKNOWN Substance Use Scientific Committee of the HIV Prevention Trials Network
Oct 19, 2012·Current Opinion in HIV and AIDS·Stefan D BaralChris Beyrer
Sep 1, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Chris BeyrerDavid D Celentano
Dec 3, 2011·Journal of Acquired Immune Deficiency Syndromes : JAIDS·M-J MilloyEvan Wood
May 30, 2013·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Masaya KatoBrian Williams
Mar 28, 2012·Current Opinion in Psychiatry·Shelly IskandarCor A De Jong
Oct 6, 2012·BMJ : British Medical Journal·Georgie J MacArthurMatthew Hickman
Apr 12, 2011·Harm Reduction Journal·Tyson VolkmannSteffanie A Strathdee
Jul 10, 2012·Harm Reduction Journal·Melissa JardineMartha Morrow
Mar 26, 2013·PloS One·Nienke van der KnaapMaria Prins
Jan 8, 2013·Journal of Multidisciplinary Healthcare·Shelly IskandarAndre van der Ven
Sep 13, 2014·Journal of the International AIDS Society·Lyuba AzbelFrederick L Altice
Jan 31, 2014·Current HIV/AIDS Reports·Nabila El-BasselSteffanie A Strathdee

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