HIV-exposed infants: rethinking care for a lifelong condition

AIDS
Nandita SugandhiChild Survival Working Group of the Interagency Task Team on the Prevention and Treatment of HIV infection in Pregnant Women

Abstract

Each year over a million infants are born to HIV-infected mothers. With scale up of prevention of mother-to-child transmission (PMTCT) interventions, only 210 000 of the 1.3 million infants born to mothers with HIV/AIDS in 2012 became infected. Current programmatic efforts directed at infants born to HIV-infected mothers are primarily focused on decreasing their risk of infection, but an emphasis on maternal interventions has meant follow-up of exposed infants has been poor. Programs are struggling to retain this population in care until the end of exposure, typically at the cessation of breastfeeding, between 12 and 24 months of age. But HIV exposure is a life-long condition that continues to impact the health and well being of a child long after exposure has ended. A better understanding of the impact of HIV on exposed infants is needed and new programs and interventions must take into consideration the long-term health needs of this growing population. The introduction of lifelong treatment for all HIV-infected pregnant women is an opportunity to rethink how we provide services adapted for the long-term retention of mother-infant pairs.

References

Feb 7, 2003·Social Science & Medicine·Edythe S HoughDarlene Mood
Oct 7, 2004·Lancet·Marie-Louise NewellUNKNOWN Ghent International AIDS Society (IAS) Working Group on HIV Infection in Women and Children
Jan 12, 2005·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·M A Marín GabrielJ T Ramos Amador
Nov 4, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Louise KuhnDonald M Thea
Sep 23, 2006·The Journal of Infectious Diseases·Susan E PachecoUNKNOWN Women and Infants Transmission Study
Nov 15, 2007·The Journal of Antimicrobial Chemotherapy·Caroline Foster, Hermione Lyall
Mar 19, 2008·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Lucie D CluverDon Operario
Jun 11, 2008·The American Journal of Clinical Nutrition·Matthew W Gillman
Jan 28, 2009·Tropical Medicine & International Health : TM & IH·Suzanne Filteau
Jun 13, 2009·Nutrition Reviews·Sheila IsanakaWafaie W Fawzi
Jan 6, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Louise KuhnGrace M Aldrovandi
Jan 6, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Roger L Shapiro, Shahin Lockman
Jan 20, 2010·Pediatrics·Paige L WilliamsUNKNOWN PACTG 219C Team
Mar 4, 2010·The Journal of Infectious Diseases·Kunjal PatelUNKNOWN P1025 team of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Aug 3, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ryan D CooperMarcello Tonelli
Sep 11, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Hans-Jürgen StellbrinkUNKNOWN ASSERT Study Group
Nov 19, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Adam AluisioCarey Farquhar
Dec 3, 2010·Bulletin of the World Health Organization·Anna CoutsoudisGurpreet Kindra
Dec 20, 2011·AIDS·Mirjam E E KretzschmarRoel A Coutinho
Mar 9, 2012·Expert Review of Anti-infective Therapy·Eliana Akemi FutataMaria Notomi Sato
May 18, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·John Odero OngʼechLaura Guay
May 23, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Eric D McCollumMina C Hosseinipour
Jul 18, 2012·The Pediatric Infectious Disease Journal·Anna DowCharles van der Horst
Nov 13, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Claudie LapriseHelen Trottier
Nov 29, 2012·Antiviral Therapy·David L Thomas
Jan 24, 2013·The Pediatric Infectious Disease Journal·Patricia A SiroisUNKNOWN Pediatric HIVAIDS Cohort Study
May 31, 2013·AIDS·Athena P KourtisDenise J Jamieson

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Citations

Oct 1, 2016·Maternal & Child Nutrition·Pili KamenjuWafaie W Fawzi
Nov 20, 2016·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Pili KamenjuWafaie W Fawzi
Jan 5, 2019·Maternal & Child Nutrition·Charlotte E LaneLinda S Adair
Oct 27, 2017·American Journal of Physical Anthropology·Rihlat Said-MohamedShane A Norris
Apr 24, 2020·New Directions for Child and Adolescent Development·Mei Tan
Mar 2, 2018·Frontiers in Immunology·Anicet Christel Maloupazoa SiawayaJoel Fleury Djoba Siawaya
Apr 30, 2016·Tropical Medicine & International Health : TM & IH·Stanzi M le RouxLandon Myer
Jan 5, 2021·AIDS·Mary J Rotheram-BorusMark Tomlinson
Jul 11, 2021·BMJ Open·Nina WeisEllen Moseholm

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