HIV Infection: Antepartum Treatment and Management

Clinical Obstetrics and Gynecology
Helene B Bernstein, Adam D Wegman

Abstract

Human immunodeficiency virus (HIV) is a retrovirus which became pandemic in the early 1980s. Since its initial characterization, advancements in diagnosis and management have transformed HIV infection from a terminal diagnosis to a chronic, manageable condition. Effective antiretroviral therapy, acting at multiple steps in the viral lifecycle, durably suppresses viral replication, preserves maternal health and prevents mother to child HIV transmission. Here, we review the salient clinical and ethical considerations of managing HIV infection during pregnancy and delivery.

References

Jul 20, 2011·The New England Journal of Medicine·Myron S CohenUNKNOWN HPTN 052 Study Team
Oct 30, 2012·American Journal of Obstetrics and Gynecology·Amanda M CotterMary J O'Sullivan
Sep 19, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·J C DunkelbergK K Leslie
May 23, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·C Eppes
May 27, 2015·BJOG : an International Journal of Obstetrics and Gynaecology·H PetersC L Townsend
Aug 5, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Tomi T KanninenStefania Asciutti
Jul 13, 2016·JAMA : the Journal of the American Medical Association·Huldrych F GünthardPaul A Volberding
Aug 8, 2017·American Journal of Obstetrics and Gynecology·UNKNOWN Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.orgJeffrey A Kuller

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Citations

Sep 22, 2018·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Natalie Gordon Lynch, Alexandra Kesler Johnson
Sep 22, 2018·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Desi M Newberry
Aug 27, 2021·Nature Reviews. Microbiology·Christina J Megli, Carolyn B Coyne

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