HIV infection in the first heart transplantation in Italy: fatal outcome. Case report

APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
F CalabreseG Thiene

Abstract

A 46-year-old man with alcoholic dilated cardiomyopathy underwent heart transplantation on November 14, 1985. It was the first cardiac transplant in Italy and at that time no HIV antibody screening test was available in this country. The patient remained in good health for 6 years postoperatively, with only one episode of rejection (type 3A). In June 1992 he died of fulminant complications of AIDS and severe chronic rejection. Neither the patient nor the organ donor belonged to any of the known risk groups for HIV infection; a retrospective analysis revealed that perioperative blood transfusions had been the vectors of transmission.

References

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Citations

Jun 6, 2003·The New England Journal of Medicine·Leonard H CalabreseRobert Zackin
Jul 31, 2001·Transplantation·P J GowD Mutimer
Oct 9, 2012·Current Opinion in Organ Transplantation·Paolo A Grossi
Nov 3, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·F AgüeroJ M Miró
Aug 28, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Antonio Hernandez ConteRoya Yumul
Sep 6, 2011·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·María Angeles CastelJosé M Miró
Jul 7, 2009·Advances in Chronic Kidney Disease·Michael G Ison
May 9, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L M KucirkaD L Segev
Mar 16, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L M KucirkaD L Segev
Oct 13, 2014·Journal of Cardiothoracic and Vascular Anesthesia·Lawrence OngAntonio Hernandez Conte
May 15, 2010·Infectious Disease Clinics of North America·Michele I MorrisMichael G Ison

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