HIV risk exposure among South African children in public health facilities

AIDS Care
O ShisanaP Dana

Abstract

The study investigates the risk exposure to HIV infection among South African children aged 2-9 years served by public health services. Together with their biological mothers, 3471 children and were recruited from inpatient and outpatient children in the Free State Province. Blood samples were taken by professional nurses and a history taken of exposure factors associated with HIV transmission. DNA testing was used to confirm biological maternity where the child was HIV-positive and the mother HIV-negative. Mother-child pairs were stratified by mother's HIV status. Exposure factors related to the child's HIV status were examined in each stratum using a chi-square test. Independent factors were then included in a multiple logistic regression model. Having an HIV-positive mother was strongly related to HIV infection in children (OR: 310; 95%CI: 148-781). However, seven HIV-positive children had HIV-negative mothers. Transmission in this group was significantly associated with breastfeeding by a non-biological mother (OR: 437; 95%CI: 53-5020), being fed with expressed breast milk from a milk room (OR: 37.6; 95%CI: 6.2-259.0), dental injection history (OR: 31.5; 95%CI: 4.5-189.4) and visits to a dentist (OR: 26.9; 95%CI: 4.4-283.5)...Continue Reading

References

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Citations

Feb 17, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rashida A FerrandElizabeth L Corbett
Jun 7, 2012·The Pediatric Infectious Disease Journal·Kristen M LittleSteven R Nesheim
Jul 1, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Craig M WilsonBret Rudy
Dec 4, 2012·Journal of the International AIDS Society·Mark F CottonShaheen Mehtar
Jul 11, 2012·AIDS Research and Treatment·Sravya KurapatiSreenivas Vishnubhatla
Dec 31, 2009·Health & Social Care in the Community·Elizabeth W Kimani-MurageKathleen Kahn
Dec 2, 2009·International Journal of STD & AIDS·M OkinyiJ J Potterat
Dec 2, 2009·International Journal of STD & AIDS·S Reid
Sep 10, 2016·Retrovirology·M-H TsaiP J R Goulder
Jul 3, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·D MyburghA Dramowski

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Methods Mentioned

BETA
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