HIV sero disclosure among men who have sex with men and transgender women on HIV pre-exposure prophylaxis

AIDS Care
J Carlo Hojilla For The iPrEx Study Team

Abstract

HIV pre-exposure prophyalxis (PrEP) might lead individuals to view serodisclosure as unnecessary. We examined the prevalence of non-disclosure and lack of knowledge of partner status in a global cohort of men who have sex with men (MSM) and transgender women (TW) enrolled in the iPrEx Open Label Extension (OLE). We calculated prevalence ratios by fitting a logistic model and estimating predicted probabilities using marginal standardization. Prevalence of non-disclosure and lack of knowledge of partner status were highest in Thailand (73% and 74%, respectively) and lowest in the USA (23% and 37%, respectively). In adjusted analyses, PrEP use was not significantly associated with non-disclosure or lack of knowledge of partner status (p-values>0.05). We found that relationship characteristics were significantly associated with both outcomes. Non-disclosure was higher among casual (adjusted prevalence ratio [aPR] 1.54, [95% confidence interval 1.24-1.84]) and transactional sex partners (aPR 2.03, [1.44-2.62]), and among partners whom participants have known only minutes or hours before their first sexual encounter (aPR 1.62, [1.33-1.92]). Similarly, participants were less likely to know the HIV status of casual partners (aPR 1.50, ...Continue Reading

References

Mar 12, 2003·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Julianne M Serovich, Katie E Mosack
Oct 31, 2003·AIDS and Behavior·María Cecilia ZeaRafael M Díaz
Aug 11, 2007·Journal of Clinical Epidemiology·A Russell LocalioJesse A Berlin
Apr 14, 2009·American Journal of Epidemiology·Hsin-Yi WengIrva Hertz-Picciotto
Jun 1, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Sarit A GolubJeffrey T Parsons
Nov 26, 2010·The New England Journal of Medicine·Robert M GrantUNKNOWN iPrEx Study Team
Apr 16, 2011·American Journal of Public Health·Carla Makhlouf ObermeyerElisabetta Pegurri
Jul 24, 2012·Lancet·Dennis AltmanRichard Parker
Jul 24, 2012·Lancet·Pamela Das, Richard Horton
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Nov 9, 2014·The Journal of Infectious Diseases·Minttu RönnHelen Ward
Jan 22, 2015·BMC Public Health·Alistair WoodwardShanthi Ameratunga

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iPrEx
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