HIV type 1 and cytomegalovirus coinfection in the female genital tract

The Journal of Infectious Diseases
Nell S LurainP Reichelderfer

Abstract

The relationship between human immunodeficiency virus (HIV) type 1 and human cytomegalovirus (CMV) was studied in blood, saliva, and cervicovaginal lavage (CVL) specimens from 33 HIV-1-infected women. An association between HIV-1 RNA and CMV DNA was found in the CVL specimens, which also were tested for cytokine levels. Women with detectable CMV DNA in CVL specimens were more likely to have higher interleukin (IL)-1 beta and IL-8 levels than were women with undetectable CMV DNA in CVL specimens. More than 1 strain of CMV was detected in specimens from 2 patients. These results suggest mechanisms by which CMV coinfection could affect HIV-1 disease progression.

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Aug 29, 2002·The Journal of Infectious Diseases·Nell S LurainBelinda Yen-Lieberman

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Citations

Mar 11, 2008·AIDS Research and Human Retroviruses·Angélique BiancottoLeonid B Margolis
Jun 8, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Toni FrederickAndrea Kovacs
Jul 21, 2009·AIDS·Jennifer A SlykerSarah L Rowland-Jones
Nov 7, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jennifer SlykerVincent Emery
Nov 23, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nyaxewo MwaanzaMatthew Bates
Nov 26, 2015·The Journal of Infectious Diseases·Sascha R EllingtonAthena P Kourtis
Jun 7, 2008·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Francy Y E CarrilloJosé M Cuevas
Jan 13, 2011·American Journal of Reproductive Immunology : AJRI·Melanie MerbahLeonid Margolis
Apr 11, 2014·Tropical Medicine & International Health : TM & IH·Matthew BatesAlimuddin Zumla
Jan 31, 2014·Journal of the International Association of Providers of AIDS Care·Joseph Y KimJeffrey D Klausner
Apr 4, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kristina AdachiUNKNOWN NICHD HPTN 040 Study Team

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