PMID: 7039491Jan 1, 1982Paper

HLA antigens in four Pacific populations with non-insulin-dependent diabetes mellitus

Annals of Human Biology
S W SerjeantsonG Le Gonidec


HLA antigen distributions in persons with normal and abnormal glucose tolerance were compared in four Pacific populations. The populations included Melanesians from the Fijian Islands, Loyalty Islands and mainland New Caledonia and Polynesians from the Wallis Islands. HLA-DR results are provided for the first time for Pacific groups. In Polynesians, HLA-B22 was increased in frequency in patients with non-insulin-dependent diabetes mellitus and also in persons with impaired glucose tolerance. However, the association was not statistically significant when corrected for the number of antigens tested. A similar increase in HLA-B22, although not significant, was seen in each of the three Melanesian populations with abnormal glucose tolerance. No other consistent increase in any HLA antigen occurred in persons with abnormal plasma glucose concentrations.


Jun 9, 1979·Lancet·D RaumK H Gabbay
Sep 1, 1978·British Medical Bulletin·W F Bodmer, J G Bodmer
Dec 2, 1978·British Medical Journal·R D Leslie, D A Pyke
Jul 17, 1971·Lancet·P H BennettM Miller
Oct 12, 1974·Lancet·J NerupA Svejgaard
Jun 17, 1967·British Medical Journal·S R Dodu
May 2, 1981·The Medical Journal of Australia·S W SerjeantsonP Zimmet
Feb 1, 1981·Diabetologia·A H BarnettD A Pyke
Nov 1, 1981·Atherosclerosis·P J Nestel, P Zimmet
Feb 9, 1980·The Medical Journal of Australia·S SerjeantsonA V Stepanas
Oct 29, 1955·Lancet·P HUGH-JONES

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Jul 1, 1992·Tissue Antigens·X GaoS W Serjeantson
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Apr 1, 1984·Tissue Antigens·D KostyuB Amos
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