HLA DQ alpha genotype and allele frequencies in Qatari population

Forensic Science International : Synergy
I M Sebetan, H A Hajar

Abstract

Genotype and allele frequencies of HLA DQ alpha locus were determined in a Qatari population sample using polymerase chain reaction (PCR) amplified DNA fragment and hybridization to allele specific oligonucleoid probes in a reversed dot blot format. Among the 200 individuals studied 21 genotypes representing products of 6 HLA DQ alpha alleles have been differentiated, and the frequencies ranged from 0.0775 to 0.2825. The observed and expected genotypes values provide a complete fit to the Hardy-Weinberg equilibrium. The power of discrimination is 0.9321 and chance of paternity exclusion is 60.9% in the Qatari population.

References

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Citations

Sep 2, 1998·Forensic Science International : Synergy·I M Sebetan, H A Hajar
Apr 26, 2006·Human Heredity·Ana M Pérez-MirandaRene J Herrera
May 25, 2005·Genetics·John J ChenGlenys Thomson
May 7, 1999·Environmental Health Perspectives·A Hirvonen

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