HMG modifications and nuclear function.

Biochimica Et Biophysica Acta
Qingchun Zhang, Yinsheng Wang

Abstract

High mobility group (HMG) proteins assume important roles in regulating chromatin dynamics, transcriptional activities of genes and other cellular processes. Post-translational modifications of HMG proteins can alter their interactions with DNA and proteins, and consequently, affect their biological activities. Although the mechanisms through which these modifications are involved in regulating biological processes in different cellular contexts are not fully understood, new insights into these modification "codes" have emerged from the increasing appreciation of the functions of these proteins. In this review, we focus on the chemical modifications of mammalian HMG proteins and highlight their roles in nuclear functions.

Citations

Jun 13, 2013·Developmental and Comparative Immunology·Youliang RaoQingmei Li
May 21, 2011·Nucleic Acids Research·Benjamin VogelRobert Hock
May 23, 2012·PloS One·Elsa Fonfría-SubirósJ Lourdes Campos
May 30, 2014·Applied Biochemistry and Biotechnology·Elnaz AmanzadehDavoud Biria
Jan 23, 2016·Journal of Proteome Research·Kenneth Robert DurbinNeil L Kelleher
Aug 23, 2011·International Journal for Parasitology·Pamela CribbEsteban Serra
May 3, 2011·Experimental Cell Research·Seyyed Hani Moussavi NikMichael Lardelli
Jun 5, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Ruiguang ZhangXiu Nie
Mar 16, 2013·Stem Cells·Pearl A Campbell, Michael A Rudnicki
Oct 26, 2012·The FEBS Journal·Jason K K Low, Marc R Wilkins
Jul 11, 2014·Molecular Aspects of Medicine·Rui KangDaolin Tang
Apr 22, 2015·Trends in Genetics : TIG·Monique G P van der Wijst, Marianne G Rots
Aug 6, 2013·Molecular Immunology·Phoebe StavrideJoseph Papamatheakis
Feb 9, 2017·PLoS Neglected Tropical Diseases·Pamela CribbRogelio Hernández-Pando
Apr 27, 2017·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Saeedeh Keyvani-GhamsariMaryam Shahhoseini
Sep 6, 2017·International Journal of Molecular Sciences·Hsiang-Cheng ChiKwang-Huei Lin
Feb 13, 2016·Microbiology and Molecular Biology Reviews : MMBR·Monika SchmollAlfredo Herrera-Estrella
Apr 9, 2011·Stroke; a Journal of Cerebral Circulation·Jiyong ZhangMasahiro Nishibori
Oct 15, 2019·The Journal of Comparative Neurology·Danye JiangMelanie A Samuel
Jan 26, 2020·International Journal of Molecular Sciences·Riccardo SgarraAnd Guidalberto Manfioletti
Jan 23, 2020·International Journal of Molecular Sciences·Robert Vignali, Silvia Marracci
Oct 27, 2018·Molecular Medicine Reports·Xiaohong ChenFang Zheng
Sep 14, 2020·Cellular and Molecular Life Sciences : CMLS·Nathalia Meireles Da CostaLuiz Eurico Nasciutti
Jun 10, 2015·Journal of Neurosurgical Anesthesiology·Jeong Min KimBon-Nyeo Koo
Nov 13, 2020·Frontiers in Immunology·Tingting ZhangLiangmeng Wei
Apr 20, 2021·Frontiers in Immunology·Yifan XiaoFang Zheng
Sep 25, 2021·Acta Biochimica Et Biophysica Sinica·Jingjing LuYinglun Han
Jul 11, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Aya M ZakiHala F Zaki

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved