Hoarseness after radical surgery with systematic lymph node dissection for primary lung cancer

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Yoshifumi SanoHironori Izutani

Abstract

Radical surgery with systematic upper mediastinal node dissection for primary lung cancer can cause recurrent laryngeal nerve (RLN) paralysis, but this is poorly reported. We retrospectively reviewed the clinical data for consecutive patients who underwent radical surgery for primary lung cancer with an observation period of at least 12 months. During follow-up, hoarseness and vocal fold movement were assessed clinically and laryngoscopically, respectively. Of the 365 patients included in this study, 22 (6.0%) experienced hoarseness as a complication. All 22 patients who experienced hoarseness had undergone upper mediastinal node dissection. Although 1 of the 22 patients refused to undergo laryngoscopy, we assessed the vocal fold movement in the remaining patients (95.5%). Among these, 5 patients (23.8%) had right RLN paralysis, and 15 (71.4%) had left RLN paralysis and showed no sign of RLN paralysis. Over 1-24 months, vocal cord movement improved in 61.1% (11/18); and over 1-28 months, hoarseness improved in 72.7% (16/22). All patients with right RLN paralysis improved without further treatment. We conclude that extensive follow-up is necessary to discern whether hoarseness is a temporary or permanent complication of radical ...Continue Reading

References

Sep 28, 2001·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·M FilaireG Escande
Mar 14, 2002·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Yi long WuWei Ou
Mar 6, 2004·The Journal of Thoracic and Cardiovascular Surgery·Ara A VaporciyanJoe B Putnam
Feb 21, 2006·The Annals of Thoracic Surgery·Morihito OkadaNoriaki Tsubota
Jul 22, 2008·The Annals of Thoracic Surgery·Domenico GalettaPierluigi Granone
May 19, 2010·The Journal of Thoracic and Cardiovascular Surgery·Jinbo ZhaoYongan Zhou
Sep 28, 2010·The Annals of Thoracic Surgery·Ollivier LaccourreyeRedha Souilamas
May 31, 2012·Seminars in Thoracic and Cardiovascular Surgery·Atsushi WatanabeTetsuya Higami
Oct 2, 2012·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·D ZhongX Yan
Jun 3, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Tomoyuki HishidaUNKNOWN Japanese Joint Committee of Lung Cancer Registry

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Citations

Jan 31, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Keiju AokageShun-Ichi Watanabe
Jun 29, 2021·Surgical Case Reports·Yasuyuki NakamuraAtsushi Watanabe
Feb 3, 2022·General Thoracic and Cardiovascular Surgery·Takahiro Homma

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