Hodgkin's lymphoma and its association with EBV and HIV infection

Critical Reviews in Clinical Laboratory Sciences
Ravnit GrewalEmmanuel-Akinola Abayomi

Abstract

Hodgkin's lymphoma (HL) constitutes a clonal expansion of what appears to be malignant B cells. Viruses are involved in its pathogenesis, such as the Epstein-Barr virus (EBV) and human immunodeficiency virus (HIV). Since these viral infections have been shown to play key roles in the pathogenesis of HL, countries with a prevalence of HIV and EBV represent interesting population targets to study the pathogenesis of HL, linking the evolution of the disease with viral infections. Usually, patients present with late stage disease often involving the bone marrow at the time of diagnosis. The present paper discusses the role of viral infection in African countries, as HL is considered to be a malignant disease characterized by an inflammatory reaction to an aberrant B cell clone that is well known as the Reed-Sternberg cell (HRS).

References

Feb 8, 1996·The New England Journal of Medicine·R KüppersK Rajewsky
Jan 1, 1996·Annals of Oncology : Official Journal of the European Society for Medical Oncology·R KüppersK Rajewsky
Nov 30, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·T MarafiotiH Stein
Apr 6, 2002·Clinics in Laboratory Medicine·Antonio M Hernandez
Aug 4, 2004·European Journal of Haematology·Vito FrancoAda Maria Florena
Mar 17, 2005·Journal of the National Cancer Institute·Gary M CliffordUNKNOWN Swiss HIV Cohort
Aug 4, 2005·Blood·Christoph MancaoWolfgang Hammerschmidt
Aug 5, 2005·The New England Journal of Medicine·Barbara J Bain
Dec 31, 2005·International Journal of Cancer. Journal International Du Cancer·Andreas BräuningerRalf Küppers
Aug 19, 2006·Blood·Robert J BiggarEric A Engels
Mar 6, 2007·Infectious Agents and Cancer·Leona W AyersJan M Orenstein
May 5, 2007·International Journal of Surgical Pathology·Rania M SeliemJudith A Ferry
May 31, 2007·Southern Medical Journal·Akshay K GuptaSteven H Swerdlow
Jun 15, 2007·Journal of the National Cancer Institute·Robert J BiggarUNKNOWN HIV/AIDS Cancer Match Study
Nov 28, 2007·Annual Review of Pathology·J L Kutok, F Wang
Nov 29, 2007·Journal of Clinical Pathology·K L GroggA Dogan
Feb 5, 2008·International Journal of Cancer. Journal International Du Cancer·Lara SteinFreddy Sitas
Apr 24, 2008·Molecular Immunology·Dörte SiemerRalf Küppers
Apr 26, 2008·International Journal of Cancer. Journal International Du Cancer·Eric A EngelsJames J Goedert
Dec 17, 2008·Blood·José I Martín-SuberoUNKNOWN Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe
Dec 17, 2008·Nature Reviews. Cancer·Ralf Küppers
Apr 22, 2009·The Journal of Experimental Medicine·Roland SchmitzRalf Küppers
Apr 25, 2009·The Cancer Journal·Franziska C EberleElaine S Jaffe
May 26, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S HohausG Leone
May 30, 2009·The Journal of Infectious Diseases·Alexander ZoufalyUNKNOWN ClinSurv Study Group
Jun 16, 2009·Clinical Lymphoma & Myeloma·Haresh Mani, Elaine S Jaffe
Oct 31, 2009·Blood·Ralf Küppers
Dec 17, 2009·Hematology·Ralf Küppers
Feb 18, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Hamakwa MantinaWendy S Stevens
Apr 30, 2010·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·R A BolarinwaM A Durosinmi
May 19, 2010·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Daniel BenharrochJacob Gopas

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Citations

Sep 22, 2018·Critical Reviews in Clinical Laboratory Sciences·Ancuta JurjIoana Berindan-Neagoe
Jul 3, 2019·Reviews in Medical Virology·Rana Jahanban-EsfahlanSamira Shirooie
Oct 31, 2020·International Journal of Molecular Sciences·Ji-Yoon NohHaiyoung Jung
May 1, 2021·International Journal of Molecular Sciences·Ting-Ting Sheu, Bor-Luen Chiang
Dec 14, 2021·Frontiers in Genetics·Minjie ShengLihua Liu

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