Hollow-Fiber flow field-flow fractionation of synthetic polymers in organic solvents

Analytical Chemistry
M van BruijnsvoortR Tijssen

Abstract

A modified polyacrylonitrile (PAN) hollow-fiber membrane from a commercial source has been applied as the separation channel in flow field-flow fractionation (FFF). With the PAN membrane fiber, the application range of flow FFF could be extended to synthetic polymers that are soluble in a variety of organic solvents. The PAN membrane was shown to be resistant to hydrophobic solvents, such as dichloromethane (DCM), tetrahydrofuran (THF), ethyl acetate, and methyl ethyl ketone (MEK), as was illustrated by the successful fractionation of different polymer standards in these solvents. The system performance was assessed using polystyrene (PS) standards with ethyl acetate as the solvent. For a 100 kDa PS standard, the average recoverywas 57%, but for standards with a molar mass of 400 kDa and higher, 100% recovery was obtained. A linear relationship between peak area and injected mass was found. The run-to-run and fiber-to-fiber repeatability was determined using 100- and 400 kDa PS standards. The repeatability appeared to be satisfactory, with relative standard deviations < 2% for the retention times and < 5% for the recoveries of the standards. Plate numbers for the 400 kDa standard on different fibers were in the order of 110. Fr...Continue Reading

References

Sep 24, 1976·Science·J C GiddingsM N Myers

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Citations

Feb 13, 2003·Journal of Chromatography. a·Pierluigi ReschiglianMyeong Hee Moon
Jun 30, 2012·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Tayssir IbrahimPhilippe Cardot
Mar 23, 2011·Journal of Chromatography. a·Andrea ZattoniPierluigi Reschiglian
Aug 18, 2009·Journal of Chromatography. a·Ju Yong LeeMyeong Hee Moon
Feb 9, 2008·Journal of Chromatography. a·Andrea ZattoniPierluigi Reschiglian
Dec 2, 2005·Journal of Separation Science·Ilyong ParkMyeong Hee Moon
Jul 26, 2002·Analytical Chemistry·Emil ChmelaAlbert van den Berg
Feb 10, 2006·Analytical Chemistry·Andrea ZattoniPierluigi Reschiglian

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