Holmium laser enucleation of the prostate (HoLEP) for small, large and giant prostatic hyperplasia: tips and tricks

Urologia
P V GlybochkoD V Enikeev

Abstract

Holmium laser enucleation of the prostate (HoLEP) allows to treat extremely large prostates (>200 cm3). The aim of the study was to compare the efficiency of HoLEP for prostates of different sizes. Four hundred and fifty-nine patients were divided into three groups: group 1 included 278 patients (<100 cm3); group 2 included 169 patients (100-200 cm3); group 3 included 12 patients (>200 cm3). The duration of enucleation in group 1 was 56.5 ± 10.7 min; in group 2 was 96.4 ± 24.9 min; in group 3 was 120.9 ± 35 min. The duration of morcellation in group 1 was 37.5 ± 7.3 min; in group 2 was 63.3 ± 11.2 min; in group 3 was 84.0 ± 25.6 min. The enucleation efficiency in group 3 (1.70 g/min) was higher (p<0.05) than in group 1 (1.05 g/min) and group 2 (1.23 g/min). Morcelation efficiency was lower in groups 1 and 2 (1.58 and 1.87 g/min, respectively) than in group 3 (2.45 g/min) (p<0.05).Follow-up period lasted 18 months. There were no significant differences (p>0.05) in International Prostate Symptom Score, Qmax, quality of life and postvoid residual volume for 1, 3, 6, 12 and 18 months after surgery. HoLEP is a safe, highly efficacious and a size-independent procedure.

Associated Clinical Trials

References

Jan 1, 1989·Lasers in Surgery and Medicine·N S Nishioka, Y Domankevitz
Jan 1, 1989·Lasers in Surgery and Medicine·L LilgeN S Nishioka
Mar 1, 1987·The Journal of Urology·S P DretlerS Murray
Jan 1, 1996·Lasers in Surgery and Medicine·J N Kabalin
Oct 1, 1996·Journal of Endourology·P J GillingM R Fraundorfer
Jul 9, 2002·Urology·Andrew H H Tan, Peter J Gilling
Oct 13, 2006·Current Opinion in Urology·P J Gilling, M R Fraundorfer
Jul 3, 2009·Current Urology Reports·Narmada P Gupta, Ajay Anand
Oct 27, 2009·Journal of Endourology·Amy E KrambeckJames E Lingeman
Nov 25, 2014·World Journal of Urology·Michael W Vincent, Peter J Gilling

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Citations

Feb 9, 2019·World Journal of Urology·Giuseppe SaittaFernando Gómez-Sancha
Feb 29, 2020·World Journal of Urology·Dmitry EnikeevOlivier Traxer
Mar 25, 2020·World Journal of Urology·Michael A ZellMitchell R Humphreys
Sep 24, 2019·International Journal of Urology : Official Journal of the Japanese Urological Association·Dmitry EnikeevPetr Glybochko

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