Holmium laser enucleation of the prostate in patients on anticoagulant therapy or with bleeding disorders

The Journal of Urology
Ehab A ElzayatMostafa M Elhilali

Abstract

We evaluated the safety and efficacy of HoLEP in patients on anticoagulation with significant obstructive symptoms secondary to BPH refractory to medical therapy. From May 1999 to October 2004, 83 patients with a mean age of 76.6 years who had symptomatic BPH and were on chronic oral anticoagulant therapy or had bleeding disorders underwent HoLEP. Mean preoperative prostate size estimated by transrectal ultrasound was 82.4 cc (range 25 to 222). A total of 14 patients underwent HoLEP without oral anticoagulant withdrawal, 34 underwent surgery with low molecular weight heparin substitution and 33 stopped anticoagulants before surgery, including 8 on antiplatelet therapy. All patients were assessed preoperatively, and 1, 3, 6 and 12 months after surgery. HoLEP was performed successfully in all patients with a mean enucleation time of 86.5 minutes (range 35 to 210). Mean morcellation time was 20.1 minutes (range 3 to 100). Peak urinary flow, post-void residual urine, International Prostate Symptom Score and quality of life score were significantly improved by 1 month after surgery and they continued to improve during subsequent followup. One patient required intraoperative platelet transfusion and 7 required blood transfusion early...Continue Reading

References

May 1, 1983·Urology·K N Van ArsdalenW W Koontz
Jan 1, 1995·The Australian and New Zealand Journal of Surgery·T E KingstonA Street
May 23, 1998·British Journal of Urology·A Chakravarti, S MacDermott
Jun 15, 1999·BJU International·C R BellR J Morgan
Sep 24, 1999·The Journal of Urology·P G BorborogluJ P Sands
Mar 29, 2001·Clinics in Geriatric Medicine·E M Hylek
Sep 22, 2001·The Medical Clinics of North America·J Spandorfer
Dec 4, 2002·BJU International·B C Fong, M M Elhilali
Jun 24, 2003·World Journal of Surgical Oncology·Ramsay L KuoJames E Lingeman
Aug 22, 2003·BJU International·J-P MeyerR Persad
Oct 9, 2003·The Journal of Urology·Harm H E van MelickTom A Boon

❮ Previous
Next ❯

Citations

Mar 30, 2007·World Journal of Urology·Andrew J Marks, Joel M H Teichman
May 6, 2011·World Journal of Urology·Mario W KramerThomas R W Herrmann
Jan 24, 2007·Current Urology Reports·Nathaniel M Fried
May 13, 2010·Current Urology Reports·Julien BergerAurelien Descazeaud
Nov 20, 2010·Current Urology Reports·Jessica MandevilleJames E Lingeman
Feb 23, 2010·JACC. Cardiovascular Interventions·Ali O Abualsaud, Mark J Eisenberg
Oct 7, 2008·Nature Clinical Practice. Urology·Abdulaziz Baazeem, Mostafa M Elhilali
Apr 9, 2008·Prostate Cancer and Prostatic Diseases·R ThurairajaD Sheehan
Jul 7, 2009·Journal of Endourology·Mark D Tyson, Lori B Lerner
Aug 1, 2006·Photomedicine and Laser Surgery
Jun 1, 2009·Therapeutic Advances in Urology·Doreen E Chung, Alexis E Te
Nov 3, 2009·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Anil Varshney, Anshuman Agarwal
Dec 1, 2010·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Amy E Krambeck
Jul 13, 2011·Urology Annals·Daniel M G SpernatHenry H Woo
Dec 24, 2010·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·Takahiro HirayamaShiro Baba
Oct 12, 2012·Current Urology Reports·Simon van Rij, Peter J Gilling
Jan 23, 2010·The Journal of Urology·Amy E KrambeckJames E Lingeman
Nov 26, 2009·Urology·Jeffery C WheatWilliam W Roberts
May 4, 2007·European Urology·Peter J GillingMark R Fraundorfer
Mar 27, 2007·The Journal of Urology·Hemendra N ShahManish B Bansal
Jan 22, 2009·BJU International·Aurélien DescazeaudUNKNOWN Committee for lower urinary tract symptoms of the French Association of Urology
Dec 19, 2007·BJU International·Peter Gilling
Mar 29, 2011·BJU International·Stavros GravasJean De La Rosette
Sep 2, 2010·BJU International·Aaron D MartinMitchell R Humphreys
Jan 15, 2010·BJU International·Abdulaziz S BaazeemMostafa M Elhilali
Jan 21, 2011·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Evangelos LiatsikosJens-Uwe Stolzenburg
Mar 17, 2007·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Alexander Bachmann, Robin Ruszat
May 27, 2014·The Journal of Urology·Daniel J CulkinDeborah J Lightner

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.