Home-based, square-stepping exercise program among older adults with multiple sclerosis: results of a feasibility randomized controlled study

Contemporary Clinical Trials
Emerson SebastiãoRobert W Motl

Abstract

There is very little known about exercise rehabilitation approaches for older adults with multiple sclerosis (MS), yet this growing segment of the MS population experiences declines in cognition and mobility associated with disease progression and aging. We conducted a RCT examining the feasibility of a 12-week, home-based Square-Stepping Exercise (SSE) program in older adults with MS. Older adults with MS (N = 26) with mild-to-moderate levels of disability were recruited and randomized into the intervention (i.e., SSE) or a minimal activity, attention-control conditions. Participants in the SSE condition received a mat for home-based practice of the step patterns, an instruction manual, and a logbook along with a pedometer for monitoring compliance. Both conditions received weekly Skype™ calls and had biweekly meetings with an exercise trainer. Feasibility was assessed based on process, resource, management and scientific outcomes. Regarding scientific outcomes, participants in both conditions completed in-lab assessments before and after the 12-week period. Twenty-five participants completed the study (96%) and the total cost of the study was $13,387.00 USD. Pedometer data demonstrated good compliance with the SSE interventio...Continue Reading

Citations

Mar 22, 2019·Cognitive and Behavioral Neurology : Official Journal of the Society for Behavioral and Cognitive Neurology·Rachel E BollaertRobert W Motl
May 12, 2020·Multiple Sclerosis : Clinical and Laboratory Research·Reza GharakhanlouFlorian Javelle
May 7, 2020·Nature Reviews. Neurology·John DeLucaBrian M Sandroff
Jul 16, 2020·Expert Review of Neurotherapeutics·Robert W Motl, Brian M Sandroff
Jul 15, 2020·Journal of Neuroengineering and Rehabilitation·Rey-Yue YuanChien-Hung Lai
Feb 8, 2021·Archives of Physical Medicine and Rehabilitation·Stephanie L SilveiraRobert W Motl
Feb 27, 2021·Frontiers in Neurology·Annette RademacherPhilipp Zimmer
May 6, 2021·Journal of Personalized Medicine·Asunción Mayoral-MorenoJosé Carmelo Adsuar
Aug 4, 2021·Multiple Sclerosis and Related Disorders·Majid Mardaniyan GhahfarrokhiRobert W Motl

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