Home-made modular diet versus semi-elemental formula in the treatment of chronic diarrhoea of infancy: a prospective randomized trial

European Journal of Pediatrics
S KolacekIan W Booth

Abstract

Considerable success in the management of chronic diarrhoea has been reported using a modular diet (MD), with gradual increments in every nutrient toward a full-strength formula. As the commercially prepared constituents are unavailable in Croatia, we have developed a home-made MD based on boiled minced chicken meat, sunflower oil emulsion, sucrose and cornflour. A full range of vitamins and minerals are added. The value of this MD was compared to a semi-elemental formula (SF) Pregomin. Eighteen infants with severe chronic diarrhoea were randomly assigned to receive either MD of SF. Both groups were comparable with respect to sex, age, and degree of malnutrition. Duration of diarrhoea, feed tolerance, anthropometry, and biochemistry were compared after 4 weeks of treatment. (1) diarrhoea was significantly shorter (3 vs 7 days; P < 0.01) and nutritional recovery started earlier (5 vs 9 days; P < 0.01) in MD group; (2) median weight gain in the SF group was 100 g/week, compared to 171 g/week in MD group (P < 0.05); (3) in two patients from the SF group, diarrhoea persisted, but they achieved complete recovery when changed to MD. A MD made in the hospital kitchen was superior to a SE formula in the treatment of chronic diarrhoea o...Continue Reading

References

Jun 29, 1978·The New England Journal of Medicine·R C Williamson
Aug 1, 1978·Journal of Human Nutrition·D E Francis
Feb 1, 1992·Journal of Pediatric Gastroenterology and Nutrition·G IaconoV Balsamo
Feb 1, 1992·The British Journal of Ophthalmology·J J Kanski
Jul 1, 1991·Journal of Pediatric Gastroenterology and Nutrition·H RömerM E Blanco
Nov 1, 1989·Journal of Pediatric Gastroenterology and Nutrition·R E KleinmanM H Ulshen
Nov 1, 1989·Journal of Pediatric Gastroenterology and Nutrition·C GodardD Nusslé
Oct 22, 1988·BMJ : British Medical Journal·N S ShahidN Rahman
Jan 1, 1988·Journal of Pediatric Gastroenterology and Nutrition·N F GaleanoC C Roy
Mar 1, 1987·Surgical Neurology·M Y Hubballah, H J Hoffman
Mar 1, 1973·American Journal of Diseases of Children·J D Lloyd-StillR M Filler
Oct 1, 1970·The Journal of Pediatrics·F LifshitzG Gutiérrez-Topete
Jan 1, 1984·Pediatric Radiology·B D FletcherS C Morrison
Jun 1, 1983·Archives of Disease in Childhood·P J AggettB E Clayton

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Citations

Nov 11, 2016·Archives of Disease in Childhood·Jane CoadDavid Widdas
Dec 1, 2017·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Teresa W JohnsonManpreet S Mundi
Dec 5, 2018·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Teresa W JohnsonAmy L Spurlock
Jan 1, 2019·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Ryan T HurtManpreet S Mundi
Feb 12, 2019·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Teresa W JohnsonManpreet S Mundi
Jul 4, 2001·The British Journal of Nutrition·M K Sim
Jul 10, 2019·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Antonia TrollipKatie Banerjee

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