Home prothrombin time monitoring: a literature analysis

American Journal of Hematology
David T YangGeorge M Rodgers

Abstract

The anticoagulant activity of warfarin sodium is monitored by the prothrombin time (PT) using the international normalized ratio (INR). Standard oral anticoagulant therapy monitoring requires frequent patient visits to physicians' offices and/or laboratories to optimize warfarin dosage. Home PT monitoring by patients can increase testing frequency and may thus decrease complications associated with oral anticoagulant therapy. Clinical studies suggest that home PT monitoring is more effective than uncoordinated management and is as effective as care through specialized anticoagulation clinics for keeping INRs within a therapeutic range. There are accurate and reliable instruments available, but paramount to the success of home PT monitoring is sound patient selection, appropriate patient training, and consistent quality control.

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Citations

Jun 24, 2008·Analytical and Bioanalytical Chemistry·Siegmund BraunHeinz Völler
Nov 11, 2009·Journal of Thrombosis and Thrombolysis·Lynn B Oertel, Edward N Libby
Sep 20, 2006·The Pharmacogenomics Journal·M Wadelius, M Pirmohamed
Feb 5, 2011·BMC Health Services Research·Syed Ghulam Sarwar Shah, Ian Robinson
Oct 5, 2010·Thrombosis Research·Sophie JonesPaul Monagle
Nov 13, 2008·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Carlos H SalvadorJosé L Monteagudo

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