PMID: 8983615Sep 1, 1996Paper

Homocysteine: an independent risk factor for the failure of vascular intervention

The British Journal of Surgery
I C CurrieW G Tennant

Abstract

Hyperhomocysteinaemia is an independent risk factor for the early development of arterial disease. Homocysteine and cardiovascular risk factors were assessed in 41 young and 25 older patients with vascular disease. As homocysteine may act by the generation of free radicals, total antioxidant capacity was measured. Hyperhomocysteinaemia was found in 29 per cent of patients but there was no difference between young and older patients. Homocysteine level was unrelated to other cardiovascular risk factors. Young age, diabetes and hyperhomocysteinaemia were independent risk factors for the failure of vascular procedures (P = 0.006). Patients with hyperhomocysteinaemia had raised total antioxidant capacity. The potential of identifying and treating a subgroup of patients with a poor prognosis deserves further study.

References

Jan 1, 1992·Journal of Inherited Metabolic Disease·H J BlomJ M Trijbels
Aug 19, 1992·JAMA : the Journal of the American Medical Association·M J StampferC H Hennekens
Apr 25, 1991·The New England Journal of Medicine·R ClarkeI Graham
Jun 1, 1989·European Journal of Vascular Surgery·D C AronsonM A Giesberts
Apr 1, 1986·The Journal of Clinical Investigation·G Starkebaum, J M Harlan
Sep 19, 1985·The New England Journal of Medicine·G H BoersP W Kloppenborg
Sep 12, 1974·The New England Journal of Medicine·L A HarkerR Ross
Sep 1, 1993·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·N P DudmanP Lundberg

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Citations

Dec 17, 1997·Clinical Biochemistry·J WooE D Janus
Dec 6, 2000·International Journal of Cardiology·K StanglG Baumann
Oct 21, 2000·Eye·S C MartinP M Dodson
Mar 4, 2006·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Alan B Lumsden, Terry W Rice
Jun 17, 2008·Journal des maladies vasculaires·C Le HelloJ Constans
May 3, 2007·Expert Opinion on Pharmacotherapy·E M FatourouD P Mikhailidis
Jul 27, 2001·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·P J BurnsA W Bradbury
Dec 6, 2005·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·E LaxdalS Aune
Dec 4, 2003·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·A A WarsiM H Lewis
Aug 4, 2004·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·E LaxdalS Aune
Sep 8, 2004·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·E LaxdalS Aune
Dec 1, 2004·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·S KhanG Stansby
Sep 25, 2002·ANZ Journal of Surgery·Yew-Ming KuanMichael J Grigg
Dec 14, 2006·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·K J HalazunJ I Spark
Apr 12, 2006·The British Journal of Surgery·S VigA Halliday
Jul 25, 2013·The Cochrane Database of Systematic Reviews·Alina AndrasMonica Hansrani

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