PMID: 4126769Nov 1, 1973

Homogenous rabbit 7S anti-IgG with antibody specificity for peptidoglycan

The Journal of Experimental Medicine
V A BokischR M KRAUSE

Abstract

The relationship between 7S anti-IgG and antibodies to streptococcal cell wall peptidoglycan was examined for four streptococcal Group C antisera. Homogeneous 7S anti-IgG components in these sera were isolated by means of an IgG immunoadsorbent column. For two of the four antisera, the anti-peptidoglycan activity of the 7S anti-IgG had specificity for the pentapeptide, L-Ala-D-Glu-gamma-L-Lys-D-Ala-D-Ala, the antigenic determinant of peptidoglycan, as well as for the Fc of IgG. Detailed studies on the 7S anti-IgG from one of the antisera revealed that the pentapeptide inhibited the coprecipitation reaction of 7S anti-IgG R3387 with antigen-antibody complexes and the precipitin reaction between 7S anti-IgG R3387 and its anti-idiotype serum.

References

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Citations

Jun 1, 1978·Arthritis and Rheumatism·J C Bennett
Sep 1, 1979·Arthritis and Rheumatism·L E Bartholomew, F N Bartholomew
Jan 1, 1981·Springer Seminars in Immunopathology·K HannestadA Husebekk
Jan 1, 1988·Springer Seminars in Immunopathology·V Agnello
Aug 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·N HenryH M McConnell
Jul 1, 1979·The Journal of Experimental Medicine·J C Brown, L S Rodkey
Sep 1, 1983·The Journal of Experimental Medicine·A N TheofilopoulosF J Dixon
Dec 1, 1986·The Journal of Experimental Medicine·M J MamulaJ B Harley
Jan 1, 1976·Scandinavian Journal of Immunology·K Hannestad, A Johannessen
Aug 10, 2000·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·H YamamotoM Kohno
Apr 1, 1984·Australian and New Zealand Journal of Medicine·P J Roberts-ThomsonJ Bradley
Jan 1, 1988·Scandinavian Journal of Rheumatology. Supplement·R C Williams
Jan 1, 1988·Scandinavian Journal of Rheumatology. Supplement·P M Johnson, H B Smalley
Jan 1, 1990·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·M W Russell, H Y Wu

Related Concepts

Anti-Antibodies
Antibody Specificity
Immune complex
Antigenic Specificity
Binding Sites, Antibody
Cell Wall
Polyglobin
Immunoglobulin Fc Fragments
Polypeptides
Pseudomurein

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