Homozygous familial hypercholesterolaemia: Spanish adaptation of the position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society. Consensus document of the Spanish Society of Arteriosclerosis (SEA) and Familial Hypercholesterolaemia Foundation (FHF)

Clínica e investigación en arteriosclerosis : publicación oficial de la Sociedad Española de Arteriosclerosis
Juan F AscasoLuis Masana

Abstract

Homozygous familial hypercholesterolaemia (HoFH) is a rare life-threatening disease characterized by markedly elevated circulating levels of low-density lipoprotein cholesterol (LDL-C) and accelerated, premature atherosclerotic cardiovascular disease (ACVD). The Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society (EAS) has recently published a clinical guide to diagnose and manage HoFH (Eur Heart J. 2014;35:2146-57). Both the Spanish Society of Atherosclerosis (SEA) and Familial Hypercholesterolaemia Foundation (FHF) consider this European Consensus document of great value and utility. However, there are particularities in our country which advise to have a Spanish adaptation of the European HoFH document in order to approximate this clinical guide to our environment. In Spain, chronic treatment with statins, ezetimibe and resins (colesevelam) has a reduced contribution in the National Health System (NHS) and is one of the few European countries where LDL apheresis is included in the Basic Service Portfolio coverage. This Spanish document also includes clinical experience in the management of these patients in our country. The Drafting Committee emphasizes the need for early identification ...Continue Reading

References

Jul 1, 1996·Heart·L RallidisG R Thompson
Oct 8, 1999·Obstetrics and Gynecology·R ThadhaniG C Curhan
Jan 5, 2002·Current Atherosclerosis Reports·A D MaraisJ C Firth
Aug 24, 2004·American Journal of Epidemiology·Melissa A AustinSteve E Humphries
Jan 12, 2007·The New England Journal of Medicine·Marina CuchelDaniel J Rader
Mar 24, 2007·Nature Clinical Practice. Cardiovascular Medicine·Anne K Soutar, Rossi P Naoumova
Aug 10, 2007·Molecular Genetics and Metabolism·Fabiana QuagliariniMarcello Arca
Mar 29, 2008·Atherosclerosis·G R Thompson, UNKNOWN HEART-UK LDL Apheresis Working Group
Apr 29, 2008·Journal of Clinical Pathology·S Kidambi, S B Patel
Apr 22, 2009·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Mahmut CokerSule Can
Jun 6, 2009·Congenital Heart Disease·Adrienne H KovacsCandice Silversides
Dec 24, 2010·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Luis Fernando Fernández-FuertesJuan Díaz Cremades
Jan 18, 2011·Pediatric Transplantation·Tevfik KüçükkartallarMunci Kalayoglu
Sep 2, 2011·Journal of Cardiovascular Translational Research·Michael IbrahimMagdi H Yacoub
Dec 27, 2011·European Journal of Radiology·Suvipaporn SiripornpitakBoonchob Pongpanich
Jan 17, 2012·Atherosclerosis·Lourdes PalaciosMarianne Stef
Jan 31, 2012·Lancet·Marina MacchiaioloAndrea Bartuli
Feb 23, 2012·Nutrition & Metabolism·M Mahmood HussainJahangir Iqbal
Mar 9, 2012·Atherosclerosis·Frederick J Raal, Raul D Santos
Sep 26, 2012·Clinical Research in Cardiology Supplements·Peter Schuff-WernerPeter Kohlschein
Sep 28, 2012·British Journal of Clinical Pharmacology·Stanley T Crooke, Richard S Geary
Oct 26, 2012·Journal of Atherosclerosis and Thrombosis·Mariko Harada-ShibaShizuya Yamashita
Jan 30, 2013·Atherosclerosis. Supplements·C Stefanutti, U Julius
Jun 14, 2013·Current Opinion in Lipidology·Ingemar Björkhem
Jun 26, 2013·European Heart Journal Cardiovascular Imaging·Ravindran RajendranNaveed Ahmed

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Citations

Jan 3, 2020·JAMA Cardiology·UNKNOWN Representatives of the Global Familial Hypercholesterolemia CommunitySamuel S Gidding
Jun 7, 2021·Clínica e investigación en arteriosclerosis : publicación oficial de la Sociedad Española de Arteriosclerosis·Teresa Arrobas VelillaUNKNOWN Investigadores del proyecto ARA

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