Horizons of nanotechnology applications in female specific cancers.

Seminars in Cancer Biology
Balney RajithaGanji Purnachandra Nagaraju

Abstract

Female-specific cancers are the most common cancers in women worldwide. Early detection methods remain unavailable for most of these cancers, signifying that most of them are diagnosed at later stages. Furthermore, current treatment options for most female-specific cancers are surgery, radiation and chemotherapy. Although important milestones in molecularly targeted approaches have been achieved lately, current therapeutic strategies for female-specific cancers remain limited, ineffective and plagued by the emergence of chemoresistance, which aggravates prognosis. Recently, the application of nanotechnology to the medical field has allowed the development of novel nano-based approaches for the management and treatment of cancers, including female-specific cancers. These approaches promise to improve patient survival rates by reducing side effects, enabling selective delivery of drugs to tumor tissues and enhancing the uptake of therapeutic compounds, thus increasing anti-tumor activity. In this review, we focus on the application of nano-based technologies to the design of novel and innovative diagnostic and therapeutic strategies in the context of female-specific cancers, highlighting their potential uses and limitations.

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Citations

Jan 29, 2020·Current Drug Metabolism·Ganji Purnachandra Nagaraju, Mohammad Amjad Kamal
Oct 17, 2019·Nanomaterials·Jacinta Oliveira PinhoMaria Manuela Gaspar
Aug 28, 2019·Seminars in Cancer Biology·Paola AielloIlaria Peluso
Feb 6, 2020·Seminars in Cancer Biology·Eunus S AliMohammad S Mubarak
Dec 25, 2019·Seminars in Cancer Biology·Haroon KhanHamed Mirzaei
May 5, 2021·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Peijie ZhouDong Qian
May 21, 2020·Current Drug Metabolism·Abu BakerMohd Sajid Khan
Jun 26, 2021·Biomaterials Science·Yin ZhongXintao Shuai

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