Mar 9, 2000

Horizontal gene transfer and the origin of species: lessons from bacteria

Trends in Microbiology
F de la Cruz, J Davies

Abstract

In bacteria, horizontal gene transfer (HGT) is widely recognized as the mechanism responsible for the widespread distribution of antibiotic resistance genes, gene clusters encoding biodegradative pathways and pathogenicity determinants. We propose that HGT is also responsible for speciation and sub-speciation in bacteria, and that HGT mechanisms exist in eukaryotes.

  • References29
  • Citations230

References

Mentioned in this Paper

Antibiotic Resistance, Microbial
Biochemical Pathway
Pathogenicity
Recombination, Genetic
Gene Transfer, Horizontal
Bioremediation
Gene Clusters
Evolution, Molecular
Antibiotics
resistance genes

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