Hormesis and immunity: A review

Acta Microbiologica Et Immunologica Hungarica
György Csaba

Abstract

The hormesis concept demonstrates that in contrast to the toxic effect of high doses of materials, irradiation, etc., low doses of them are beneficial and, in addition, help to eliminate (prevent) the deleterious effect of high doses given after it. By this effect, it is an important factor of (human) evolution protecting man from harmful impacts, similarly to the role of immunity. However, immunity is also continuously influenced by hormetic effects of environmental [chemical (pollutions), physical (background irradiations and heat), etc.] and medical (drugs and therapeutic irradiations) and food interactions. In contrast to earlier beliefs, the no-threshold irradiation dogma is not valid in low-dose domains and here the hormesis concept is valid. Low-dose therapeutic irradiation, as well as background irradiations (by radon spas or moderately far from the epicenter of atomic bomb or nuclear facilities), is rather beneficial than destructive and the fear from them seems to be unreasonable from immunological point of view. Practically, all immune parameters are beneficially influenced by all forms of low-dose radiations.

References

Jan 1, 1992·Japanese Journal of Cancer Research : Gann·M MifuneH Tanooka
Dec 1, 1990·International Journal of Radiation Biology·M MineS Kondo
May 1, 1987·Health Physics·S Z LiuJ B Sun
May 1, 1987·Health Physics·K S Nambi, S D Soman
Apr 19, 1996·Journal of Toxicology and Environmental Health·M NagarkattiA Brooks
Aug 24, 1999·Nutrition and Cancer·T D Luckey
Mar 4, 2000·Toxicological Sciences : an Official Journal of the Society of Toxicology·G J Wang, L Cai
Mar 15, 2000·Journal of Applied Toxicology : JAT·P A Parsons
Apr 4, 2000·Human & Experimental Toxicology·E J Calabrese, L A Baldwin
Jan 5, 2001·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·D McGeoghegan, K Binks
Mar 31, 2001·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·A Rico
Jan 5, 2002·The Science of the Total Environment·Y T LeeW J Chen
Oct 22, 2002·AJR. American Journal of Roentgenology·Bernard L Cohen
Jun 18, 2003·Critical Reviews in Toxicology·Shu-Zheng Liu
Jul 30, 2003·Physics in Medicine and Biology·Xiao-Dong LiuShu-Zheng Liu
Mar 19, 2004·Risk Analysis : an Official Publication of the Society for Risk Analysis·Daniel L Hunt, Dale Bowman
May 11, 2004·Journal of Radiation Research·Shuji KojimaHirokazu Ishida
Jan 28, 2005·The British Journal of Radiology·L E Feinendegen
Feb 18, 2006·International Journal of Radiation Biology·Ruchi PandeyKrishna B Sainis
Feb 24, 2006·Radiation Research·Mareyuki Takahashi, Shuji Kojima
May 23, 2006·Drug Discovery Today·Walter E Stumpf
Oct 4, 2006·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Shuji Kojima
Apr 11, 2007·Cellular Immunology·Hongwei RenToru Abo
Aug 25, 2007·Brain, Behavior, and Immunity·E MerlotW Otten
Oct 24, 2007·Experimental Gerontology·J G SørensenV Loeschcke
Nov 15, 2007·Infectious Agents and Cancer·Nikolai A Shevchuk, Sasa Radoja
Dec 7, 2007·Radiation and Environmental Biophysics·Aneta ChedaMarek K Janiak
Dec 29, 2007·Ageing Research Reviews·Mark P Mattson
Apr 17, 2008·Journal of Radiation Research·Hiroko NakatsukasaShuji Kojima
May 16, 2008·Human & Experimental Toxicology·Rodney R Dietert, Michael S Piepenbrink
Jul 24, 2008·Dose-response : a Publication of International Hormesis Society·Charles L Sanders, Bobby R Scott
Jul 24, 2008·Dose-response : a Publication of International Hormesis Society·Shu-Zheng Liu
Jan 10, 2009·Acta Microbiologica Et Immunologica Hungarica·J G Sinkovics
Apr 1, 2003·Nonlinearity in Biology, Toxicology, Medicine·John A Bukowski, R Jeffrey Lewis
Mar 12, 2010·Dose-response : a Publication of International Hormesis Society·Alexander M Vaiserman
Apr 20, 2010·Journal of Pediatric Gastroenterology and Nutrition·G GalbiatiA Dhawan
Jul 17, 2010·Biomechanics and Modeling in Mechanobiology·R J H ClootsM G D Geers
Aug 6, 2010·Journal of Physiological Anthropology·Katsuyasu Kouda, Masayuki Iki

❮ Previous
Next ❯

Citations

Aug 1, 2021·International Journal of Radiation Biology·Annum DawoodColin Seymour

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Canadian Journal of Public Health = Revue Canadienne De Santé Publique
F C PACE
La Prensa médica mexicana
H MANJARREZ
Advances in Biological and Medical Physics
J W HOWLAND, S L WARREN
L'unión médicale du Canada
O DUFRESNE
© 2022 Meta ULC. All rights reserved