Hormonal and anthropometric predictors of bone mass in healthy elderly men: major effect of sex hormone binding globulin, parathyroid hormone and body weight

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
G Martínez Díaz-GuerraM Díaz-Curiel

Abstract

Osteoporosis in men is a significant health problem, and factors associated with bone mass are being investigated. Although osteoporosis is a typical feature of hypogonadism, the influence of testosterone levels and other hormonal factors on bone mass of eugonadal males is unknown. Our aim was to identify several anthropometric and hormonal predictors that could be responsible for the variability in bone mineral density (BMD) in healthy men. One hundred elderly men (age 68 +/- 7 years) were investigated in this cross-sectional study. BMD was measured by dual-energy X-ray absorptiometry (DXA) at the lumbar spine and femoral sites (femoral neck, Ward's triangle, trochanter, intertrochanter and total femur). Anthropometric measures were obtained including: weight, height, body mass index (BMI), waist-hip ratio and testicular volume. Hormonal data measures were total, free and bioavailable testosterone, dihidrotestosterone, estradiol, sex hormone binding globulin (SHBG), insulin-like growth factor I (IGF-I), intact parathyroid hormone (iPTH) and 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). One subject was excluded because primary hypogonadism was found. SHBG levels were increased in 53.5% of men, and 8% showed a mild increase in iPTH le...Continue Reading

Citations

Nov 21, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R F LopesM L F Farias
Mar 26, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·G R ChiuJ B McKinlay
Jul 13, 2005·Clinical Rheumatology·Demet OfluogluGulseren Akyuz
Jan 31, 2002·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Alvin M Matsumoto
Feb 9, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Hubert BlainClaude Jeandel
Feb 16, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Marilia Brasilio Rodrigues CamargoMarise Lazaretti-Castro
Apr 16, 2013·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Ioannis KyvernitakisPeyman Hadji
Oct 11, 2011·Revista clínica española·F Hawkins Carranza
Aug 2, 2011·Joint, Bone, Spine : Revue Du Rhumatisme·Julien PaccouBernard Cortet
Oct 20, 2009·Trends in Endocrinology and Metabolism : TEM·Filip CallewaertDirk Vanderschueren
Aug 5, 2015·Archives of Osteoporosis·Hrafnhildur L RunolfsdottirOlafur S Indridason
Mar 15, 2005·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Christian MeierJohn A Eisman
Aug 10, 2005·Joint, Bone, Spine : Revue Du Rhumatisme·Işik KeleşErtan Batislam
Aug 20, 2005·American Journal of Physical Anthropology·Benjamin C CampbellKenneth L Campbell
Jul 20, 2005·Archives of Andrology·I KelesE Batislam
Jan 19, 2006·American Journal of Physiology. Endocrinology and Metabolism·William A BaumanErnest Schwartz
Oct 18, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity·Benjamin Leder
Nov 7, 2003·The Journal of Clinical Endocrinology and Metabolism·Luigi GennariRanuccio Nuti
Dec 7, 2006·The Journal of Clinical Endocrinology and Metabolism·Sundeep Khosla
Feb 6, 2010·The Journal of Clinical Endocrinology and Metabolism·Griet VanbillemontJean-Marc Kaufman
Jun 8, 2004·The Journal of Clinical Endocrinology and Metabolism·Luigi GennariMaria Luisa Brandi
Nov 4, 2016·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Gina N WoodsUNKNOWN Osteoporotic Fractures in Men (MrOS) Study Research Group
May 16, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B HanuschH K Datta

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