PMID: 2116945Jun 1, 1990Paper

Hormonal changes in patients with polycystic ovarian disease after ovarian electrocautery or pituitary desensitization

Clinical Endocrinology
A A GadirR W Shaw

Abstract

Eleven patients with polycystic ovarian disease (PCO) were treated by laparoscopic ovarian electrocautery and nine with a long-acting luteinizing hormone releasing agonist (LHRH-A) for 8 weeks. Both groups showed equivalent significant decreases in their 6-h mean values of luteinizing hormone (LH) and testosterone (T) measured in 25 samples collected every 15 min. Patients treated with ovarian electrocautery showed significant increases in their 6-h mean values of follicle stimulating hormone (FSH) and insulin with variable oestradiol (E2) responses. The magnitude of change following treatment was significantly greater for LH than for FSH. Buserelin medication did not cause persistent significant changes in the levels of insulin or FSH but it did cause a significant reduction in the 6-h mean values of E2. We conclude that LH is the gonadotrophin primarily affected after pituitary desensitization and ovarian electrocautery. Furthermore, there is no direct correlation between the levels of circulating insulin and testosterone in patients with PCO.

References

Feb 1, 1987·American Journal of Obstetrics and Gynecology·E Greenblatt, R F Casper
Aug 1, 1987·British Journal of Obstetrics and Gynaecology·H Gjønnaess, N Norman
Sep 1, 1987·The Journal of Clinical Endocrinology and Metabolism·A DunaifA Dobrjansky
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Citations

Jan 1, 1995·Lasers in Surgery and Medicine·E M KaaijkF van der Veen
Mar 12, 2004·Metabolism: Clinical and Experimental·Marzieh SalehiLeonid Poretsky
Apr 1, 1996·Baillière's Clinical Endocrinology and Metabolism·J Holte
Apr 1, 1996·Baillière's Clinical Endocrinology and Metabolism·B W Donesky, E Y Adashi
Aug 1, 1995·Ceská gynekologie·J Zivný
May 1, 1996·The Journal of the American Association of Gynecologic Laparoscopists·B I Rose
Mar 1, 1991·British Journal of Obstetrics and Gynaecology·A Abdel GadirR W Shaw
Nov 18, 2003·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·N P Johnson, Kaye Wang
Sep 2, 1999·Human Reproduction·P J MarsdenR Taylor
Nov 1, 1993·British Journal of Obstetrics and Gynaecology·P VandekerckhoveT W Harada
Dec 1, 1993·British Journal of Obstetrics and Gynaecology·A H BalenH S Jacobs
Mar 1, 1993·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·A Abdel GadirR W Shaw
Mar 1, 1993·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·J VerhelstC Mahler
Sep 1, 1994·Journal of Veterinary Internal Medicine·B R MooreK W Hinchcliff
Nov 26, 2002·Obstetrical & Gynecological Survey·Joop S E LavenBart C J M Fauser

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