Hormonal contraception and HIV disease progression.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Elizabeth M Stringer, Erik Antonsen

Abstract

The majority of the 15.4 million human immunodeficiency virus (HIV)-infected women worldwide are of child-bearing age and need access to contraception. Hormonal methods of contraception are safe, acceptable, and effective in preventing unwanted pregnancies. Many published studies have examined the impact of hormonal contraception on HIV disease acquisition and transmissibility. Far fewer have investigated the relationship between hormonal contraception and HIV disease progression. This review examines available data on this relationship from clinical, animal, and immunological studies. Several clinical studies suggest an overall effect but are not definitive, and the mechanisms behind HIV disease progression are unclear. Animal and immunological data suggest that immunomodulation by hormonal contraceptive methods may affect the immune response to HIV infection. Additional work is needed in this area to elucidate the possible relationship between hormonal methods for birth control and progression to acquired immunodeficiency syndrome in HIV-infected women.

References

Jan 1, 1988·Journal of Steroid Biochemistry·L DanelJ P Revillard
Jun 9, 1993·JAMA : the Journal of the American Medical Association·D B ClemetsonS Hillier
Oct 1, 1996·Nature Medicine·P A MarxN J Alexander
Sep 2, 1998·Molecular and Cellular Endocrinology·S PasanenP Tuohimaa
Sep 24, 1998·British Journal of Obstetrics and Gynaecology·R French, P Brocklehurst
Mar 20, 1999·Science·C C WhitacreP A O'Looney
May 11, 1999·Journal of Acquired Immune Deficiency Syndromes : JAIDS·C C WangJ K Kreiss
Dec 10, 1999·American Journal of Reproductive Immunology : AJRI·G LaskarinE R Podack
Aug 10, 2002·The Journal of Allergy and Clinical Immunology·Javier Chinen, William T Shearer
Jan 9, 2003·American Journal of Reproductive Immunology : AJRI·Gordana LaskarinDaniel Rukavina
Sep 15, 2004·The Journal of Experimental Medicine·Jason M BrenchleyDaniel C Douek
May 4, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Jared M BaetenAnn Duerr
May 4, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Bikgit H B van BenthemMaria Prins
Jul 5, 2005·The Journal of Infectious Diseases·Zabrina L BrummeP Richard Harrigan
Jan 10, 2006·International Immunopharmacology·Daichi KatagiriKikuo Onozaki
Mar 1, 2006·Sexually Transmitted Diseases·Heidi W ReynoldsLaura Johnson
Apr 6, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ludo LavreysJulie Overbaugh
Apr 18, 2006·Current Opinion in Immunology·Laurie E HarringtonCasey T Weaver
Jun 20, 2006·Immunity·Casey T WeaverKenneth M Murphy
Dec 7, 2006·AIDS·Charles S MorrisonUNKNOWN Hormonal Contraception and the Risk of HIV Acquisition (HC-HIV) Study Group
Feb 20, 2007·Experimental Gerontology·Victor AppayLaura Papagno
Mar 16, 2007·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Laura M EnomotoAdriana Weinberg
Apr 7, 2007·AIDS·Barbra A RichardsonGrace C John-Stewart
Aug 21, 2007·AIDS·Mark D WestonFazel Randera
Aug 11, 2007·American Journal of Obstetrics and Gynecology·Elizabeth M StringerJeffrey S A Stringer
Oct 17, 2007·Reproductive Health Matters·Iqbal H Shah, Lale Say
Feb 6, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Grant C HughesEdward A Clark

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Citations

Nov 4, 2010·European Journal of Clinical Pharmacology·Dario CattaneoEmilio Clementi
Jul 10, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Gretchen S Stuart
Nov 24, 2011·International Journal of Biological Sciences·Galileo EscobedoJorge Morales-Montor
Dec 5, 2012·Reproductive Health Matters·Sarah MacCarthySofia Gruskin
Dec 14, 2011·Autoimmunity Reviews·Sabine Oertelt-Prigione
Oct 27, 2009·Journal of Reproductive Immunology·Jiri MesteckyRashada C Alexander
Nov 23, 2010·American Journal of Reproductive Immunology : AJRI·Catherine A Blish, Jared M Baeten
Jan 13, 2011·American Journal of Reproductive Immunology : AJRI·Brenna L Anderson, Susan Cu-Uvin
Mar 13, 2014·American Journal of Reproductive Immunology : AJRI·Victor H FerreiraCharu Kaushic
Apr 14, 2010·American Journal of Reproductive Immunology : AJRI·Charu KaushicAisha Nazli
Dec 3, 2014·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·K Kivimets, A Uuskula
Sep 29, 2015·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Adriana WeinbergSusan E Cohn

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