PMID: 9556085Apr 29, 1998Paper

Hormonal regulation of appetite and food intake

Annals of Medicine
A L Hirschberg

Abstract

Several clinical disorders are strongly influenced by hormones involved in appetite and weight regulation. Obesity and eating disorders are of major importance, because they are associated with severe morbidity and considered to be among the greatest health problems in the Western world today. This review describes recent findings in hormonal regulation of food intake by substances acting both centrally, such as corticotropin-releasing factor, neuropeptide Y and leptin, and peripherally, such as cholecystokinin and somatostatin. Sex hormones and glucocorticoids play an important role in long-term regulation of metabolism. The role of these hormones in appetite and weight changes during life as well as during pregnancy and lactation is discussed. Furthermore, the development of obesity and eating disorders is influenced, in particular, by steroid hormones. Treatment with sex hormones, as in hormone replacement therapy, affects appetite and weight and may have beneficial effects in preventing android obesity. Currently, there is great effort in developing endogenous neurohumoral substances into effective drugs for the treatment of obesity and eating disorders. Leptin and neuropeptide Y analogues are of interest as potential antio...Continue Reading

References

Mar 1, 1979·Physiology & Behavior·G N Wade, J M Gray
Jan 1, 1979·Monographs on Endocrinology·J D Baxter, G G Rousseau
May 18, 1979·JAMA : the Journal of the American Medical Association·E Barrett-ConnorM H Criqui
Nov 1, 1978·Endocrinology·G N Wade, J M Gray
Jan 1, 1976·The Journal of Clinical Endocrinology and Metabolism·M KrotkiewskiP Björntorp
Sep 1, 1992·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·B P LukertR G Robinson
Sep 1, 1992·Child Abuse & Neglect·E E Sabotta, R L Davis
Jul 1, 1992·American Journal of Obstetrics and Gynecology·R KarlssonB von Schoultz
Aug 1, 1992·The American Journal of Clinical Nutrition·E ForsumK Westerterp
Aug 1, 1992·Metabolism: Clinical and Experimental·P MårinP Björntorp
Jan 1, 1992·The American Journal of Clinical Nutrition·G A Bray
Sep 1, 1991·Brain Research Bulletin·T W Castonguay
Jan 1, 1991·Life Sciences·E PhillippJ C Krieg
Nov 1, 1990·The Journal of Clinical Endocrinology and Metabolism·M Rebuffé-ScriveP Björntorp
Jul 1, 1990·The American Journal of Physiology·M H Montrose, H Murer
Feb 1, 1989·The Journal of Clinical Endocrinology and Metabolism·A B LoucksS S Yen
Mar 1, 1989·The British Journal of Psychiatry : the Journal of Mental Science·P H Robinson
Jul 1, 1989·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·M Rebuffé-ScriveP Björntorp
Jul 1, 1986·The Journal of Clinical Endocrinology and Metabolism·A L VillanuevaR W Rebar
Jan 1, 1986·Neuroscience and Biobehavioral Reviews·S P Grossman
Jan 1, 1987·Annals of the New York Academy of Sciences·P Rosso
Sep 15, 1988·The New England Journal of Medicine·T D Geracioti, R A Liddle
May 1, 1986·The American Journal of Physiology·A WohlwendL Orci
Sep 1, 1986·Metabolism: Clinical and Experimental·M Rebuffé-ScriveP Björntorp
Nov 1, 1985·The American Journal of Clinical Nutrition·S C WoodsB Jeanrenaud
Jun 1, 1985·The Journal of Clinical Investigation·M Rebuffé-ScriveP Björntorp
Oct 1, 1985·Clinical Pharmacology and Therapeutics·R L AtkinsonD L Kaiser
Jun 1, 1973·Metabolism: Clinical and Experimental·P Beck
Jun 1, 1982·Pharmacology, Biochemistry, and Behavior·A S Levine, J E Morley
Sep 12, 1980·Science·J E Morley, A S Levine

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Citations

Jul 20, 2002·Journal of Biomechanics·B Schmölzer, W Müller
Mar 2, 2002·Domestic Animal Endocrinology·C R BarbK L Houseknecht
Dec 24, 2004·Critical Reviews in Food Science and Nutrition·Pervin BasaranMehmet Numan Tamer
Oct 5, 2002·Journal of the American Academy of Child and Adolescent Psychiatry·Katarzyna BisagaAgnes H Whitaker
Jan 28, 2012·Maturitas·Angelica Lindén Hirschberg
Dec 25, 2003·Obesity Research·Valerio Cigaina, Angelica L Hirschberg
Feb 12, 2008·The American Journal of Medicine·Alan N Elias, Heather Hofflich
Jun 24, 2004·Nutrition·Karl SudiWolfram Müller
May 12, 2004·Peptides·Sarah F Leibowitz, Katherine E Wortley
Feb 3, 2005·Nutritional Neuroscience·Leonidas H DuntasGeorge Panotopoulos
Mar 31, 2004·Analytical Biochemistry·P MistríkJ M Allen
Apr 4, 2006·Current Biology : CB·Gil B CarvalhoSeymour Benzer
Oct 25, 2016·Acta histochemica·Sungin LeeWan Hee Kim
Feb 28, 2001·Diabetes, Obesity & Metabolism·B BaranowskaM Borowiec
Aug 10, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J T DourmashkinS F Leibowitz
Mar 13, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·N F ChuE B Rimm
Oct 18, 2000·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·A Hedberg, S Rössner
Apr 19, 2002·The Journal of Pharmacology and Experimental Therapeutics·Chun-Su YuanHan H Aung
Jul 29, 2005·Critical Reviews in Clinical Laboratory Sciences·Paolo M Suter
May 14, 2005·Endocrinology·Yukari DateMasamitsu Nakazato
Jul 14, 2000·American Journal of Physiology. Endocrinology and Metabolism·M H VickersP D Gluckman
Jun 7, 2021·The Journal of Nutrition·Thomas SevrinMarie-Cécile Alexandre-Gouabau

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