Hormonal stimulation of lactose synthetase in mammary carcinoma

Science
W L McGuire

Abstract

A transplantable rat mammary carcinoma (R3230AC) synthesizes significant quantities of the mammary gland enzyme lactose synthetase in the immature virgin female rat. In this hormonal environment, mammary glands do not synthesize the enzyme. Prolactin further stimulates the enzyme activity in the tumors to levels found only in mammary glands of rats in late pregnancy or during lactation.

References

Feb 1, 1968·Proceedings of the National Academy of Sciences of the United States of America·K BrewR L Hill

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Citations

Feb 1, 1971·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E HeiseG Bacigalupo
Jun 1, 1976·Molecular and Cellular Endocrinology·P R ReddyH G Williams-Ashman
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Jan 1, 1982·European Journal of Cancer & Clinical Oncology·J M OrloskiD K Liu
Jan 15, 1986·International Journal of Cancer. Journal International Du Cancer·K Krohn, M Helle
Jul 1, 1992·British Journal of Addiction·J BrownF K Del Boca
Oct 8, 1997·Journal of Child Psychology and Psychiatry, and Allied Disciplines·R BrownJ Stevenson
Jan 14, 2011·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Andres De Los Reyes

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