Hormonally active phytochemicals and vertebrate evolution

Evolutionary Applications
Max R Lambert, Thea M Edwards

Abstract

Living plants produce a diversity of chemicals that share structural and functional properties with vertebrate hormones. Wildlife species interact with these chemicals either through consumption of plant materials or aquatic exposure. Accumulating evidence shows that exposure to these hormonally active phytochemicals (HAPs) often has consequences for behavior, physiology, and fecundity. These fitness effects suggest there is potential for an evolutionary response by vertebrates to HAPs. Here, we explore the toxicological HAP-vertebrate relationship in an evolutionary framework and discuss the potential for vertebrates to adapt to or even co-opt the effects of plant-derived chemicals that influence fitness. We lay out several hypotheses about HAPs and provide a path forward to test whether plant-derived chemicals influence vertebrate reproduction and evolution. Studies of phytochemicals with direct impacts on vertebrate reproduction provide an obvious and compelling system for studying evolutionary toxicology. Furthermore, an understanding of whether animal populations evolve in response to HAPs could provide insightful context for the study of rapid evolution and how animals cope with chemical agents in the environment.

References

Oct 2, 1981·Science·P J BergerP D Gardner
May 1, 1995·Journal of Animal Science·N R Adams
May 1, 1993·The Journal of Steroid Biochemistry and Molecular Biology·L MarkiewiczE Gurpide
Dec 29, 2000·Phytochemistry·J B Harborne, C A Williams
May 2, 2001·Proceedings of the National Academy of Sciences of the United States of America·J W Thornton
Jul 10, 2001·Journal of Chemical Ecology·N ChavesJ C Escudero
Sep 1, 2001·The Journal of Steroid Biochemistry and Molecular Biology·E DornstauderA Jungbauer
Dec 14, 2001·Biochemical and Biophysical Research Communications·L MilanesiR Boland
Feb 22, 2002·Hormones and Behavior·Lisa A Henry, Diane M Witt
Apr 19, 2002·Current Opinion in Plant Biology·Brenda Winkel-Shirley
Aug 3, 2002·Environmental Health Perspectives·D G Joakim Larsson, Lars Förlin
Aug 21, 2003·Journal of Agricultural and Food Chemistry·Annalisa RomaniDaniela Heimler
Oct 1, 1954·The Biochemical Journal·J D BIGGERS, D H CURNOW
Apr 16, 2004·Toxicological Sciences : an Official Journal of the Society of Toxicology·Stefan O MuellerKenneth S Korach
Aug 25, 2004·Journal of Ethnopharmacology·S G SpargJ van Staden
Sep 11, 2004·Psychoneuroendocrinology·Thomas J HuberHinderk M Emrich
Jun 4, 2005·Science·Matthew D AnwayMichael K Skinner
Oct 6, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Ming Zhu FangChung S Yang
May 26, 2006·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Joanne L ParrottL Mark Hewitt
May 26, 2006·Journal of Toxicology and Environmental Health. Part B, Critical Reviews·Mark E McMasterJoanne L Parrott
Jul 5, 2006·Environmental Health Perspectives·Taisen IguchiYoshinao Katsu
Oct 5, 2006·The Plant Journal : for Cell and Molecular Biology·Senthil SubramanianOliver Yu
Jan 26, 2007·The Prostate·Jen-Jih Chen, Hong-Chiang Chang
Feb 7, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·L JiC C Helbing
Jun 6, 2007·Future Oncology·Jan H J MartinPaul N Nelson
Aug 7, 2007·General and Comparative Endocrinology·Cynthia CorbittGeorge E Bentley

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Citations

Nov 21, 2017·Evolutionary Applications·Steven P BradyJohn W Bickham
Jun 9, 2020·Ecology Letters·Phoebe D EdwardsRudy Boonstra
Jan 14, 2021·Environmental Monitoring and Assessment·Kelly L SmallingMichael J Adams

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